Claude Sebag

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AIMS The choice of resynchronization therapy between with (CRT-D) and without (CRT-P) a defibrillator remains a contentious issue. Cause-of-death analysis among CRT-P, compared with CRT-D, patients could help evaluate the extent to which CRT-P patients would have additionally benefited from a defibrillator in a daily clinical practice. METHODS AND RESULTS(More)
Complete atrioventricular block (AVB) following radiotherapy has been reported rarely, usually after high dose mediastinal irradiation for Hodgkin's disease or lung or breast carcinoma. We report six new cases of episodic complete infranodal AVB, requiring permanent pacemaker implantation. The mean age was 48-years old (ranging from 25-60) at the first(More)
Since its introduction at the beginning of the 1980s, radiofrequency ablation of accessory atrioventricular pathways has become method because of its excellent results and the indications have increased to cases in which only symptomatic improvement is the objective. These advances have been made possible by technical innovations to the generators of the(More)
The effects of beta-blockers and calcium-channel blockers on cardiopulmonary response during exercise are not well characterized. Sixteen sedentary patients with essential hypertension underwent a randomized, double-blind, cross-over study comparing atenolol and diltiazem sustained-release 300 mg, each administered during 6 weeks, after a 15-day run-in(More)
A case of a congenital aneurysm of the right anterior sinus of Valsalva (ASV) extending into the septum is reported. The patient, a 20 year old male Central-African, presented with syncopal complete atrioventricular block (AVB) or recent onset. There were no clinical or radiological signs of associated cardiac disease. After implantation of a pacemaker, the(More)
Radiofrequency currents are the reference physical agent for endocavitary ablation, especially of supraventricular tachycardias. They are delivered in a continuous mode or sinusoidal waves. Because of the high frequency between 200 and 3,000 kHz there is no stimulation of the neuromuscular cells. The mechanism of the resulting lesion is essentially related(More)
Sixty patients with recurrent inducible sustained ventricular tachycardia were prospectively treated with nadolol (40 or 80 mg/day). Old myocardial infarction was present in 43 patients and dilated cardiomyopathy in 12. In group I (n = 36), nadolol was given alone, whereas in group II (n = 24), previously ineffective treatment with amiodarone was continued(More)