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Species va r i a t ions in m e m b r a n e lipid class c o m p o s i t i o n can be s tudied by analys is o f h ighly purif ied subce l lu l a r pa r t i cu la tes and m o r e rap id ly by analys is o f w h o l e o rgans . Th i s r epo r t p r e sen t s ana lyses o f lipid c lasses in h u m a n , bovine , rat , m o u s e , and f rog lungs . T h e close s(More)
In an attempt to elucidate the mechanism by which the rate of fatty acid oxidation is tuned to the energy demand of the heart, the effects of changing intramitochondrial ratios of [acetyl-CoA]/[CoASH] and [NADH]/[NAD+] on the rate of beta-oxidation were studied. When 10 mM L-carnitine was added to coupled rat heart mitochondria to lower the ratio of(More)
Both the central and peripheral nervous system of the cockroach Periplaneta americana contain gamma-aminobutyric acid (GABA) and glutamate decarboxylase (GAD). In the central ganglia of the cockroach, an average of more that 60 mumoles of GABA are formed from glutamate (Glu) per gram wet weight of tissue per hour. This activity level of the GAD apoenzyme is(More)
Hyperprolinemic PRO/Re mice have been studied as potential models for hyperprolinemia in man. In addition to high proline levels, some heretofore unreported amino acid abnormalities in the brains of PRO/Re mice are described. The T-maze and shuttlebox learning abilities of PRO/Re mice were compared with those of CD-1 mice having normal proline levels.(More)