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  • Patrick Lacolley, Carlos Labat, A Pujol, Claude Delcayre, Athanase Benetos, Michel E. Safar
  • Medicine
  • Circulation
  • 2002 (First Publication: 26 November 2002)
  • Background—Previous studies have demonstrated the development of cardiac fibrosis in aldosterone (Aldo)–salt hypertensive rats. Our aim was to determine the effects of Aldo and the Aldo receptorExpand
  • Valérie J P Robert, Christophe Heymes, Josephine Silvestre, Alia Sabri, Bernard Swynghedauw, Claude Delcayre
  • Medicine
  • Hypertension
  • 1999 (First Publication: 1 April 1999)
  • This study tests the hypothesis that aldosterone induces cardiac fibrosis through an increase of cardiac angiotensin II (Ang II) AT1 receptor levels, thereby potentiating the fibrotic effect of AngExpand