Claude Abdallah

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Valproic acid (VPA) is one of the widely prescribed antiepileptic drugs in children with multiple indications. VPA-induced coagulopathy may occur and constitute a pharmacological and practical challenge affecting pre-operative evaluation and management of patients receiving VPA therapy. This review summarizes the different studies documenting the incidence,(More)
Among the different results that may be achieved with premedication such as amnesia, optimization of preoperative conditions and prevention of physiological stress, the primary aim in children is anxiolysis. Almost 50% of children show signs of significant preoperative fear and anxiety 1 . It has been reported that there are correlations between heart rate,(More)
Chlorhexidine is an antiseptic agent, commonly used, in many different preparations, and for multiple purposes. Despite its superior antimicrobial properties, chlorhexidine is a potentially allergenic substance. The following is a review of the current evidence-based knowledge of allergic reactions to chlorhexidine associated with surgical and(More)
PURPOSE Controlling the cerebral and systemic hemodynamic responses to laryngoscopy and tracheal intubation may play a role in determining clinical outcome in pediatric neurosurgical patients. This study compared the effects of remifentanil and fentanyl on cerebral blood flow velocity (CBFV) and hemodynamic profile during laryngoscopy and tracheal(More)
Acute epiglottitis is a life-threatening disorder with serious implications to the anesthesiologist because of the potential for laryngospasm and irrevocable loss of the airway. Acute epiglottitis can occur at any age. Early diagnosis with careful and rapid intervention of this serious condition is necessary in order to avoid life-threatening complications.
Pseudocholinesterase (PChE), also known as plasma cholinesterase, is a serine hydrolase capable of hydrolyzing esters including acetylcholine, succinylcholine, mivacurium and ester type local anesthetics such as procaine, chloroprocaine, tetracaine, cocaine and heroin. PChE is synthesized by the liver, and is found in the plasma, the pancreas, the heart and(More)