Claribel Luciano-Montalvo

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Cystatin (CSTB, also known as stefin B), a cysteine protease inhibitor, recently was found to be down-regulated in the proteome of uninfected and HIV-1-infected placental macrophages (PMs) and associated with restricted HIV-1 replication in PM but not in monocyte-derived macrophages (MDMs). We investigated CSTB interactions with signal transducer and(More)
Mononuclear phagocytes (MP; monocytes, tissue macrophages, and dendritic cells) are reservoirs, vehicles of dissemination, and targets for persistent HIV infection. However, not all MP population equally support viral growth. Such differential replication is typified by the greater ability of placental macrophages (PM), as compared to blood borne(More)
The generation of signals following engagement of cell surface receptors is an ordered process that requires tight regulation as spurious signals could result in unwanted, and possibly deleterious, cellular responses. Like other cell surface receptors, stimulation of a mast cell via the high affinity IgE receptor (FcepsilonRI) causes multiple biochemical(More)
BACKGROUND The TRAMIL program aims to understand, validate and expand health practices based on the use of medicinal plants in the Caribbean, which is a "biodiversity hotspot" due to high species endemism, intense development pressure and habitat loss. The antibacterial activity was examined for thirteen plant species from several genera that were(More)
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