Clare Smith

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UNLABELLED Amyloid-beta (Abeta) imaging with N-methyl-(11)C-2-(4'-methylamino-phenyl)-6-hydroxy-benzothiazole ((11)C-6-OH-BTA-1; also known as (11)C-PIB) shows a robust increase in cortical binding in Alzheimer's disease (AD). The aim of this study was to explore the clinical potential of Abeta imaging for the diagnosis of AD by comparison of the accuracy(More)
Previous research has indicated that parents who raise children having disabilities report greater emotional distress than other parents. To investigate the association between symptoms of depression and maternal behaviors, interactions between 48 mothers and children having disabilities were rated. Measures of maternal depression and child functioning were(More)
Adolescents' trajectories of impulsive and hostile behaviors provide a dynamic index of risk for the emergence of Cluster B (antisocial and borderline) personality disorders in early adulthood. In the current study, we tested the hypothesis that preoccupied states of mind in the Adult Attachment Interview would increase both the level and rate of growth in(More)
This paper discusses ways of enabling visually impaired and physically disabled people to compose and perform music. The usage and adaptation of existing software-based composition systems are described, in the context of education work undertaken by the Drake Music Project-a charity which aims to facilitate disabled people in making music via technology.(More)
Background 18F-FDG is a glucose analogue that is taken up by a wide range of malignancies. 18F-FDG PET-CT is now firmly established as an accurate method for the staging and restaging of various cancers. However, 18F-FDG also accumulates in normal tissue and other non-malignant conditions, and some malignancies do not take up F18-FDG or have a low affinity(More)
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