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  • Katherine E Sleeman, Howard D Kendrick, David J. Robertson, Clare M. Isacke, Alan Ashworth, Matthew J Smalley
  • Medicine, Biology
  • The Journal of cell biology
  • 2007 (First Publication: 1 January 2007)
  • The role of estrogen in promoting mammary stem cell proliferation remains controversial. It is unclear if estrogen receptor (ER)–expressing cells have stem/progenitor activity themselves or if theyExpand
  • Katherine E Sleeman, Howard D Kendrick, Alan Ashworth, Clare M. Isacke, Matthew J Smalley
  • Medicine, Biology
  • Breast Cancer Research
  • 2005 (First Publication: 1 February 2005)
  • IntroductionBreast cancer is thought to arise in mammary epithelial stem cells. There is, therefore, a large amount of interest in identifying these cells. The breast is a complex tissue consistingExpand
  • Lucy East, Clare M. Isacke
  • Biology, Medicine
  • Biochimica et biophysica acta
  • 2002 (First Publication: 19 September 2002)
  • The mannose receptor family comprises four glycoproteins each of which is a type I transmembrane receptor with an N-terminal cysteine-rich domain, a single fibronectin type II (FNII) domain and eightExpand
  • Selma Esseghir, Sarah Katrina Todd, +4 authors Clare M. Isacke
  • Biology, Medicine
  • Cancer research
  • 2007 (First Publication: 15 December 2007)
  • By screening a tissue microarray of invasive breast tumors, we have shown that the receptor tyrosine kinase RET (REarranged during Transfection) and its coreceptor GFR alpha 1 (GDNF receptor familyExpand
  • Susan C. Wheatley, Clare M. Isacke, Philip H. Crossley
  • Biology, Medicine
  • Development
  • 1993 (First Publication: 1 October 1993)
  • CD44 is a multifunctional adhesion protein that acts as a major receptor for the hygroscopic extracellular matrix component, hyaluronan. This receptor-ligand binding directly mediates at least someExpand