Clare Jackson

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OBJECTIVE To explore trial participants' responses to receiving a summary of the results of a trial in pregnancy. DESIGN Qualitative study with semistructured interviews. PARTICIPANTS 20 women who had when pregnant participated in the ORACLE trial of antibiotics for preterm labour and preterm rupture of the membranes and requested a copy of the trial(More)
BACKGROUND Quantification of ventricular volume by steady state free precession (SSFP) cardiovascular magnetic resonance is accurate and reproducible. Normal values exist for adults, but are lacking for children.We sought to establish normal values for left and right ventricular volumes, mass and function in healthy children by using SSFP. METHODS AND(More)
A method to automatically plan acquisition of magnetic resonance images aligned with the cardiac axes is presented. Localiser images are acquired with a mean short axis orientation calculated from a group of (n=50) adult patients. These images are segmented using the expectation maximization algorithm. The borders of the ventricular blood pools are found(More)
Effective LDL-cholesterol (LDL-C) reduction improves vascular function and can bring about regression of atherosclerosis. Alterations in endothelial function can occur rapidly, but changes in atherosclerosis are generally considered to occur more slowly. Vascular magnetic resonance imaging (MRI) is a powerful technique for accurate non-invasive assessment(More)
BACKGROUND Increasingly, the sharing of study results with participants is advocated as an element of good research practice. Yet little is known about how receiving the results of trials may impact on participants' perceptions of their original decision to consent. OBJECTIVE We explored participants' views of their decision to consent to a clinical trial(More)
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