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BACKGROUND Suicide rates vary by occupation but this relationship has not been frequently studied. AIMS To identify the occupations with significantly high suicide rates in England and Wales in 2001-2005 and to compare these with rates from previous decades. METHOD Mortality data from death registrations in England and Wales over the calendar years(More)
OBJECTIVE To assess the effect of the UK Committee on Safety of Medicines' announcement in January 2005 of withdrawal of co-proxamol on analgesic prescribing and poisoning mortality. DESIGN Interrupted time series analysis for 1998-2007. SETTING England and Wales. DATA SOURCES Prescribing data from the prescription statistics department of the(More)
OBJECTIVES To quantify mortality associated with sepsis in the whole population of England. DESIGN Descriptive statistics of multiple cause of death data. SETTING England between 2001 and 2010. PARTICIPANTS All people whose death was registered in England between 2001 and 2010 and whose certificate contained a sepsis-associated International(More)
BACKGROUND Antidepressant prescribing has been increasing in England. Studies in other countries suggest that while this may be associated with reduced suicide rates, it may also be associated with increased fatal poisoning from antidepressant drugs. We therefore conducted an ecological study to assess the association between prescription rates for(More)
BACKGROUND Paracetamol (acetaminophen) poisoning is the leading cause of acute liver failure in Great Britain and the United States. Successful interventions to reduced harm from paracetamol poisoning are needed. To achieve this, the government of the United Kingdom introduced legislation in 1998 limiting the pack size of paracetamol sold in shops. Several(More)
BACKGROUND The incidence of and mortality from alcohol-related conditions, liver disease and hepatocellular cancer (HCC) are increasing in the UK. We compared mortality rates by country of birth to explore potential inequalities and inform clinical and preventive care. DESIGN Analysis of mortality for people aged 20 years and over using the 2001 Census(More)
Prescription of atypical antipsychotics has increased in recent years. There have also been changes in the guidance on using older drugs, particularly the restriction in the use of thioridazine. We analysed deaths due to poisoning involving antipsychotics in England and Wales, 1993-2002, by age, sex, intent, and agents involved. We also studied(More)
Sepsis-associated mortality in England: an analysis of multiple cause of death data ▸ Prepublication history and additional material for this paper is available online. To view these files please visit the journal online ABSTRACT Objectives: To quantify mortality associated with sepsis in the whole population of England.