Clara Sacchini

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OBJECTIVE To determine the possible association between single umbilical artery (SUA) at 11-14 weeks of gestation and the incidence of chromosomal abnormalities. METHODS Color flow imaging of the fetal pelvis was used to determine the number of umbilical arteries in 717 fetuses immediately before chorionic villus sampling for karyotyping at 11-14 weeks'(More)
OBJECTIVE To examine the association between absence of the nasal bone at the 11-14-week ultrasound scan and chromosomal defects. METHODS Ultrasound examination was carried out in 3829 fetuses at 11-14 weeks' gestation immediately before fetal karyotyping. At the scan the fetal crown-rump length (CRL) and nuchal translucency (NT) thickness were measured(More)
OBJECTIVE To determine the value of measuring fetal ear length at 11-14 weeks of gestation in screening for chromosomal defects. METHODS The fetal ear length was measured in 450 fetuses immediately before chorionic villus sampling for karyotyping at 11-14 weeks of gestation. RESULTS The median gestational age was 12 (range, 11-14) weeks. The fetal ear(More)
The most effective sonographic marker of trisomy 21 and other chromosomal defects is increased nuchal translucency (NT) thickness at 11-14 weeks. Extensive studies over the last decade have examined the methodology of measuring NT, the development of the necessary algorithms for calculating the individual patient risk for trisomy 21 by NT in combination(More)
The accurate assessment of gestational age is very important in everyday practice. By the use of multiple regression analysis, in a longitudinal study, ultrasound dating-curves were calculated for the crown-rump length, biparietal diameter, femur length, humerus length, binocular distance and transverse cerebellar diameter. All the examined parameters(More)
OBJECTIVE To determine the value of measuring fetal femur and humerus length at 11-14 weeks of gestation in screening for chromosomal defects. METHODS Femur and humerus lengths were measured using transabdominal ultrasound in 1018 fetuses immediately before chorionic villus sampling for karyotyping at 11-14 weeks of gestation. In the group of(More)
OBJECTIVE The aim of the present observational study was to evaluate the feasibility of a morphological scan and determine the detection rate of fetal organs, structures and systems in the first trimester of pregnancy. METHODS 977 single pregnant women attending our Fetal Medicine Section to undergo first trimester screening for aneuploidies were enrolled(More)
A pregnant woman, at 28 weeks' gestation, has been observed ultrasonographically. A complex mass arising from the umbilical cord was detected. Color Doppler imaging demonstrated the vascular nature of the mass and the strictly connection with the three umbilical vessels. Color Doppler ultrasound provides useful informations for a correct assessment of the(More)
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