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OBJECTIVE Concern for potential adverse effects of antiretroviral (ARV) chemotherapy used to prevent mother-to-child HIV transmission has led the US Public Health Service to recommend long-term follow-up of ARV-exposed children. Nucleoside reverse transcriptase inhibitor ARV agents can inhibit DNA polymerase gamma, impairing mitochondrial DNA (mtDNA)(More)
Internships in library and information studies (LIS) for the New Information Society are reexamined taking into consideration four concepts: (i) international and (ii) interdisciplinary that allow them to expand beyond the local and disciplinary, and (iii) intentional and (iv) interconnected, that draw attention to their purpose, the learning process and(More)
OBJECTIVE We sought to document gender differences in lymphocyte subsets and plasma RNA levels in a pediatric cohort with presumed minimal hormonal differences (on the basis of age). METHODS Blood samples from antiretroviral therapy-treated, HIV-infected children (n = 158) and HIV-uninfected children (n = 1801) who were enrolled in the Women and Infants(More)
OBJECTIVE The purpose of this study was to assess the risk of perinatal HIV-1 transmission in women who are coinfected with herpes simplex virus-2 (HSV-2). STUDY DESIGN We performed a nested case-control study of 26 women whose HIV-1 was transmitted to their infants and 52 control subjects whose HIV-1 was not transmitted. We assessed antepartum serologic(More)
The species-area curve, which describes the relationship between the number of observed species in a geographical region and the area of the region, plays a central role in biogeography. Beyond its scientific importance, the species-area curve is commonly used to assess the loss of species due to habitat loss. When the species-area curve is estimated from(More)