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OBJECTIVE Concern for potential adverse effects of antiretroviral (ARV) chemotherapy used to prevent mother-to-child HIV transmission has led the US Public Health Service to recommend long-term follow-up of ARV-exposed children. Nucleoside reverse transcriptase inhibitor ARV agents can inhibit DNA polymerase gamma, impairing mitochondrial DNA (mtDNA)(More)
OBJECTIVE We sought to document gender differences in lymphocyte subsets and plasma RNA levels in a pediatric cohort with presumed minimal hormonal differences (on the basis of age). METHODS Blood samples from antiretroviral therapy-treated, HIV-infected children (n = 158) and HIV-uninfected children (n = 1801) who were enrolled in the Women and Infants(More)
OBJECTIVE The purpose of this study was to assess the risk of perinatal HIV-1 transmission in women who are coinfected with herpes simplex virus-2 (HSV-2). STUDY DESIGN We performed a nested case-control study of 26 women whose HIV-1 was transmitted to their infants and 52 control subjects whose HIV-1 was not transmitted. We assessed antepartum serologic(More)
The species-area curve, which describes the relationship between the number of observed species in a geographical region and the area of the region, plays a central role in biogeography. Beyond its scientific importance, the species-area curve is commonly used to assess the loss of species due to habitat loss. When the species-area curve is estimated from(More)
Miguel Abal Mohamed Abdelrahim Kohtaro Abe Yaser Abu El-Sameed Muhanned Abu-Hijleh Waqar Ahmed Vassilis Aidinis Jason Akulian Omar Al Rawas Kenneth Altman Stefan Andreas Somborac-Bačura Anita Raffaele Antonelli-Incalzi Toru Arai Shambhu Aryal Kazuhisa Asai Carl Victor Asche Babak Asghari Rendell Ashton Najib Ayas Imran Aziz Bruno Balbi Adam Barczyk Matthew(More)