Clara B. Fernandes

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In recent times, infectious diseases are posing to be a major healthcare issue. The contagious nature of these diseases makes it imperative to develop logical solutions for early diagnosis and containment of these diseases. Traditional techniques suffer from limitations, including laborious sample preparation, bulky instrumentation and slow data readout. In(More)
The aim of the present study was to investigate the potential of a phospholipid-based microemulsion formulation for parenteral delivery of anticancer drug, etoposide. The microemulsion area was identified by constructing pseudoternary phase diagrams. The prepared microemulsions were subjected to different thermodynamic stability tests. The microemulsion(More)
With an increase in lifespan and changing population demographics, the incidence of central nervous system (CNS) diseases is expected to increase significantly in the 21st century. Contrary to common belief, it is recognized that neurodegenerative diseases may be multisystemic in nature and this presents numerous difficulties for the potential treatment of(More)
Amphotericin B (AmB) is a polyene antibiotic, widely used against life threatening systemic infections with fungi such as Candida albicans or Aspergillus fumigates as well as parasite such as Leishmania donovani. Until recently, AmB has been administered parenterally; however, this approach has been associated with significant infusion-related side effects(More)
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