Claire Lincoln

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BACKGROUND The growing postnatal human heart maintains electromechanical function while undergoing substantial changes of cellular topology and myocardial architecture. The capacity for growth and remodeling of ventricular myocardium in adaptation to the hemodynamic changes of early infancy later declines. This decline is associated with changes in(More)
BACKGROUND Acute right ventricular (RV) restrictive physiology after tetralogy of Fallot repair results in low cardiac output and a prolonged stay in the intensive care unit (ICU). However, its mechanism remains uncertain. METHODS AND RESULTS In the first 24 hours after tetralogy of Fallot repair (n=11 patients), serial prospective measurements were(More)
SUMMARY We have studied 17 patients diagnosed in life as having absent left atrioventricular connection (14 patients) or an imperforate left atrioventricular valve (three patients). Ten patients presented below the age of 3 months with tachypnoea, mild cyanosis, and heart failure. Seven patients, including two with moderate and one with severe pulmonary(More)
SUMMARY Between 1973 and 1978, 120 patients with transposition of the great arteries had a modification of Mustard's operation designed to avoid damage to the sinus and atrioventricular nodes. Of these, 88 had an atrial baffle alone from which nine hospital and four late deaths occurred (total mortality 14.8%); 32 had additional closure of ventricular(More)
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