Claire Domon

Learn More
Axin2/Conductin/Axil and its ortholog Axin are negative regulators of the Wnt signaling pathway, which promote the phosphorylation and degradation of beta-catenin. While Axin is expressed ubiquitously, Axin2 mRNA was seen in a restricted pattern during mouse embryogenesis and organogenesis. Because many sites of Axin2 expression overlapped with those of(More)
TCF and SOX proteins belong to the high mobility group box transcription factor family. Whereas TCFs, the transcriptional effectors of the Wnt pathway, have been widely implicated in the development, homeostasis and disease of the intestine epithelium, little is known about the function of the SOX proteins in this tissue. Here, we identified SOX9 in a SOX(More)
During mammalian development, the Cdx1 homeobox gene exhibits an early period of expression when the embryonic body axis is established, and a later period where expression is restricted to the embryonic intestinal endoderm. Cdx1 expression is maintained throughout adulthood in the proliferative cell compartment of the continuously renewed intestinal(More)
We have recently isolated and characterized several flower-specific clones from a sunflower cDNA library [ 1]. Two of these clones, SF2 and SF18, were shown to hybridize exclusively to RNA from anthers in the late developmental stages (none of the two RNA species is detected in anthers from a closed sunflower inflorescence). The two mRNAs, which are(More)
The wheat mitochondrial (mt) cox3 has been localized and sequenced. The gene exists as a single copy in the wheat mt master chromosome and is transcribed into a single 1.2 kb RNA, whose extremities have been mapped. Comparison of the wheat and Oenothera cox3 sequences gives ambiguous indications concerning the amino acid coded by the codon CGG. Upstream and(More)
We have isolated and sequenced an anther-specific gene from sunflower which encodes an 800-nucleotide transcript detectable in the peripheral anther cells. It contains an intron of 2615 bp, which separates the first exon (77 bp) coding for a putative signal peptide of 21 amino acids, from the second exon (563 bp) coding for a 100 amino acid polypeptide. The(More)
We describe here the nucleotide sequence of an anther-specific gene (sf18) from sunflower, encoding a proline- and glycine-rich polypeptide with a hydrophobic amino-terminus (signal peptide). The gene is split by a 211 by intron and is partially related to another anther-specific gene (sf2) from sunflower with which it shares important sequence stretches in(More)
Members of the Wnt family of signaling proteins have diverse and important functions during development in a wide range of multicellular organisms (Cadigan and Nusse, 1997; Moon et al., 1997). Genetic and biochemical studies have identified the factors involved in Wnt signal transduction and have demonstrated that this signaling pathway is evolutionarily(More)
La muqueuse intestinale est responsable de la double fonction de digestion/absorption des aliments et de barri6re selective vis-fi-vis des ElEments contenus dans la lumi6re intestinale. Ces deux fonctions sont Etroitement liEes et dependent du maintien de l'intEgritE physique et fonctionnelle de l'EpithElium digestif. Le g6ne Cdx-2, dont l'expression est(More)
  • 1