Claire-Alix Garin

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BACKGROUND Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder commonly associated with insulin resistance (IR). Previous studies indicate about the expression of molecules involved in the insulin pathway in endometria of women with PCOS-IR. Therefore, the aim of the present study was to evaluate the effect of insulin and testosterone in the(More)
We have studied the effects of lovastatin, an inhibitor of hydroxy-methylglutaryl-CoA-reductase, on cultures of Trypanosoma cruzi epimastigotes. It inhibits growth at 10 and 30 micrograms per ml; these effects are reverted by 100 microM of squalene, but not by 100 microM of cholesterol. Lovastatin at the same amounts inhibits [14C]acetate incorporatin into(More)
First observation of subcutaneous phycomycosis observed in Gabon. Diagnosis was made by histological study. Biopsy permitted isolation of B. haptosporus. Sensitivity in vitro against ketoconazole was 1 microgram/ml. The patient cured with 33 g of ketoconazole in 84 days.