Clair M. Callan

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This study compares the emergence and recovery characteristics of sevoflurane, desflurane, and halothane in children undergoing adenoidectomy with bilateral myringotomy and the insertion of tubes. Eighty children 1-7 yr of age were studied. Thirty minutes prior to the induction of anesthesia, all patients received 0.5 mg/kg midazolam orally. Patients were(More)
UNLABELLED Despite mounting clinical evidence that supports its safety, the question of the potential adverse effects of sevoflurane on renal function continues to generate some controversy. This study retrospectively evaluated pooled renal laboratory data from 22 different clinical trials that compared sevoflurane with three widely used anesthetics. The(More)
BACKGROUND Under certain circumstances in the clinical setting, contact of the anesthetic sevoflurane with a CO2 absorbent (e.g., soda lime, Baralyme) leads to the formation of a degradant designated as pentafluoroisopropenyl fluoromethyl ether (PIFE; Compound A). Previous studies have shown that the kidney is the primary target organ for toxicity in the(More)
Patient empowerment is a new concept in health care that has now been extended to the domain of patient safety. Within the framework of the development of the new World Health Organization (WHO) Guidelines on Hand Hygiene in Health Care, the authors conducted a review of the literature from 1997 to 2008 to identify the evidence supporting programs aimed at(More)
To the Editor: The following letter was mailed to Chiefs of Anesthesiology and Directors of Pharmacies on January 22, 1997. On November 18, 1996, Abbott Laboratories initiated a voluntary recall on one [1] lot of Sevo£urane, Lot 10-590-DK. This action was taken following the evaluation of a bottle of Sevo£urane with an uncharacteristic pungent odor.(More)
STUDY OBJECTIVE To determine the potential clinical significance of admixtures of thiopental sodium and acidic drugs, which are used during induction of general anesthesia and can cause the formation of particles of thiopental. DESIGN Using an infusion setup similar to that used for a rapid-sequence induction of general anesthesia, injection of either(More)