Claes Lennmarken

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BACKGROUND Patients who are given general anaesthesia are not guaranteed to remain unconscious during surgery. Knowledge about the effectiveness of current protective measures is scarce, as is our understanding of patients' responses to this complication. We did a prospective case study to assess conscious awareness during anaesthesia. METHODS 11785(More)
BACKGROUND Explicit recall (ER) is evident in approximately 0.2% of patients given general anaesthesia including muscle relaxants. This prospective study was performed to evaluate if cerebral monitoring using BIS to guide the conduction of anaesthesia could reduce this incidence significantly. PATIENTS AND METHODS A prospective cohort of 4945 consecutive(More)
The clinical symptoms of 55 patients with primary fibromyalgia (PF) were studied and compared with 30 patients with rheumatoid arthritis (RA). The PF patients expressed a more intense feeling of illness than did the RA patients. Stiffness occurred just as often in PF as in RA. Trigger points occurred less frequently in RA patients. Muscular fatigue appeared(More)
BACKGROUND This study evaluated whether it is possible to estimate the severity of pre-eclampsia through in vitro measurements of platelet and granulocyte parameters. EXPERIMENTAL PROTOCOL Eighteen pre-eclamptic women in the third-trimester of pregnancy and 11 women in the third-trimester of normal pregnancies were included in the study. Three to 12(More)
Six subjects susceptible to malignant hyperthermia (MHS) and seven control subjects exercised for 4 min at 120% of their calculated maximal oxygen uptake on a bicycle ergometer. Mean (SEM) muscle pH, measured with a needle-tipped electrode in the vastus lateralis muscle, decreased from a resting value of 7.16 (0.04) to 6.78 (0.04) after exercise in the(More)
This study was done at the Linköping University Hospital, Sweden, to assess the quality of care given to patients undergoing outpatient anaesthesia. A questionnaire was given to all adult patients (> 15 years old) immediately on admission to the outpatients' surgical ward and the patients were asked to answer all the questions, if necessary with the help of(More)
BACKGROUND A correlation between deep anesthesia (defined as time with Bispectral Index (BIS) <45; T(BIS <45)) and death within 1 yr after surgery has previously been reported. In order to confirm or refute these findings, we evaluated T(BIS <45) as an independent risk factor for death within 1 and 2 yr after surgery and also the impact of malignancy, the(More)
Intraoperative awareness with subsequent recall is a rare but serious complication with an incidence of 0.1-0.2%. In approximately one third of the patients who have experienced awareness, late severe psychiatric sequelae may develop. The psychiatric symptoms in these patients fulfil the diagnostic criteria for post traumatic stress disorder. To prevent(More)
Dynamic posturography, a new method to study postural stability in humans, was performed in 11 healthy volunteers before administration of midazolam 0.1 mg/kg body weight i.v., and repeated subsequently at 45, 105 and 165 min. Results indicate that balance was affected significantly (P less than 0.008) up to 45 min after i.v. midazolam and did not return to(More)
The study was designed to evaluate nitrogen needs in severely injured patients during the first week after trauma. Thirty-nine patients aged from 18 to 65 years with a burn or fractures of more than two long bones were studied. Energy requirements were given parenterally as fat and glucose in isocaloric amounts. The patients were randomized into five groups(More)