Ck Naidu

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Estrogen receptor alpha (ERα) plays a key role in the malignancy of breast cancer. Therefore, inhibitors for ERα can act as useful agents for the treatment of breast cancer. In the present study, we describe docking, toxicity prediction as a rational strategy for identification of novel hits or leads. Pubmed search showed, 76(More)
One of the most common cancer types faced by the women around the world is breast cancer. Among the several low, moderate and high penetrance genes conferring susceptibility to breast cancer, PTEN is one which is known to be mutated in many tumor types. In this study, we predicted and analyzed the impact of three deleterious coding non-synonymous single(More)
One of the common malignancies faced by women around the world is breast cancer. Risk factors for breast cancer include both genetic and non-genetic. Variants in some of the candidate genes are a common risk factor in breast cancer. These genetic variants associated with breast cancer can be classified as high, moderate or low based on relative risk [1].(More)
  • Gajanan Trymbakappa Lamdhade, Vidya Bharati Mahavidyalaya, CK Naidu
  • 2015
The influence of CO 2 gas concentration on the transport properties of SnO 2-10Al 2 O 3-10TiO 2 oxide thick films has been studied. From the X-RD spectra the average crystallite size of the samples is found to be of the order of 10.80 nm to 56.05 nm and shows polycrystalline and granular nature. For a fixed concentration of gas the sensitivity decreases(More)
BACKGROUND Ras genes are thought to play an important role in human cancer since they have been found to be activated frequently in several types of tumors including breast cancer, where the overall incidence of K-RAS oncogene activation is 0-10%. Evaluation of K-RAS gene not only for mutational frequency but also for mutation types in this downstream(More)
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