Cindy X. Chen

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MK-0869 (aprepitant), a potent substance P antagonist, is the active ingredient of EMEND which has recently been approved by the FDA for the prevention of chemotherapy-induced nausea and vomiting. Early clinical tablet formulations of MK-0869 showed significant food effects on absorption, suggesting that formulation could have a significant role in(More)
We present a valid-time extension of SQL and investigate its efficient implementation on an Object-Relational database system. We propose an approach where temporal queries are expressed using a point-based time model, which only requires minimal extensions to SQL:1999. Our prototype system called TENORS (for Temporal ENhanced Object-Relational System) maps(More)
The skyline query can help identify the “best” objects in a multi-attribute dataset. During the past decade, this query has received considerable attention in the database research community. Most research focused on computing the “skyline” of a dataset, or the set of “skyline objects” that are not dominated by any other(More)
Online dating sites have become popular platforms for people to look for potential romantic partners. Many online dating sites provide recommendations on compatible partners based on their proprietary matching algorithms. It is important that not only the recommended dates match the user’s preference or criteria, but also the recommended users are(More)
BACKGROUND Post-operative ileus (POI) is a transient bowel dysmotility after operation. We have previously shown that laparotomy alone significantly delayed gastrointestinal (GI) transit, compared to anesthesia alone. The GI transit was further delayed after laparotomy plus intestinal manipulation. Dai-Kenchu-to (DKT), an herbal medicine, has been used for(More)
Due to the inherent immune evasion properties of the HIV envelope, broadly neutralizing HIV-specific antibodies capable of suppressing HIV infection are rarely produced by infected individuals. We examined the feasibility of utilizing genetic engineering to circumvent the restricted capacity of individuals to endogenously produce broadly neutralizing(More)
The semantic web envisions a World Wide Web in which data is described with rich semantics and applications can pose complex queries. Ontologies, a cornerstone of the semantic web, have gained wide popularity as a model of information in a given domain that can be used for many purposes, including enterprise integration, database design, information(More)
of the Dissertation Data Models and Query Languages of Spatio-Temporal Information by Cindy Xinmin Chen Doctor of Philosophy in Computer Science University of California, Los Angeles, 2001 Professor Carlo Zaniolo, Chair In this dissertation, we extend database models and query languages to support spatio-temporal information, including representations for(More)