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  • M M Wolfson, B E Forman, K T Calden, W J Dupree, R J Johnson, R A Boldi +4 others
  • 2004
tables, and brief excerpts from this work in scientific and educational works is hereby granted provided that the source is acknowledged. Any use of material in this work that is determined to be " fair use " under Section 107 of the U.S. Copyright Act or that satisfies the conditions specified in Section 108 of the U.S. Copyright Act (17 USC §108, as(More)
BACKGROUND HER-2/neu, which encodes a receptor tyrosine kinase, is amplified and overexpressed in 20%-25% of human breast cancers. Such tumors are often resistant to hormone therapy. Despite a general inverse association between HER-2/neu amplification/overexpression and estrogen receptor (ER) and/or progesterone receptor (PR) expression, a fraction of(More)
INTRODUCTION Amplification of the HER-2 receptor tyrosine kinase has been implicated in the pathogenesis and aggressive behavior of approximately 25% of invasive human breast cancers. Clinical and experimental evidence suggest that aberrant HER-2 signaling contributes to tumor initiation and disease progression. Transforming growth factor beta (TGF-beta) is(More)
  • Paul Denholm, Robert Margolis, Bryan Palmintier, Clayton Barrows, Eduardo Ibanez, Lori Bird +27 others
  • 2014
NOTICE This report was prepared as an account of work sponsored by an agency of the United States government. Neither the United States government nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information,(More)
  • W J Dupree, M M Wolfson, R J Johnson, K E Theriault, B E Forman, B Boldi +1 other
  • 2002
tables, and brief excerpts from this work in scientific and educational works is hereby granted provided that the source is acknowledged. Any use of material in this work that is determined to be " fair use " under Section 107 of the U.S. Copyright Act or that satisfies the conditions specified in Section 108 of the U.S. Copyright Act (17 USC §108, as(More)
Genomic expression profiling has greatly improved our ability to subclassify human breast cancers according to shared molecular characteristics and clinical behavior. The logical next question is whether this technology will be similarly useful for identifying the dominant signaling pathways that drive tumor initiation and progression within each breast(More)
  • Beth Hurst, Cindy Wilson, Genny Cramer, Dow Jones Interactive
  • 2001
Because professional teaching portfolios serve as visual representations of teachers, their contents should be determined by individual teachers and should vary significantly. The authors provide guidelines for constructing such portfolios. Our first exposure to using a portfolio outside the realm of the college classroom was provided by a student who took(More)
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