Cindy Eckart

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Neural activity in mesolimbic brain regions scales with stimulus novelty but the mechanistic role of neurotransmitters in this process remains unclear. Here, we used magnetoencephalography together with psychopharmacological stimulation in healthy humans to demonstrate that the neuronal dynamics of novelty processing are temporally adaptive and flexible. In(More)
BACKGROUND In Parkinson's disease the degree of motor impairment can be classified with respect to tremor dominant and akinetic rigid features. While tremor dominance and akinetic rigidity might represent two ends of a continuum rather than discrete entities, it would be important to have non-invasive markers of any biological differences between them in(More)
We used electroencephalography (EEG) together with psychopharmacological stimulation to investigate the role of dopamine in neural oscillations during working memory (WM). Following a within-subjects design, healthy humans either received the dopamine precursor L-Dopa (150 mg) or a placebo before they performed a Sternberg WM paradigm. Here, sequences of(More)
Working memory (WM) can be defined as the ability to maintain and process physically absent information for a short period of time. This vital cognitive function has been related to cholinergic neuromodulation and, in independent work, to theta (4-8Hz) and alpha (9-14Hz) band oscillations. However, the relationship between both aspects remains unclear. To(More)
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