Chyuan Samuel Hsieh

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Development of the appropriate CD4+ T helper (TH) subset during an immune response is important for disease resolution. With the use of naïve, ovalbumin-specific alpha beta T cell receptor transgenic T cell, it was found that heat-killed Listeria monocytogenes induced TH1 development in vitro through macrophage production of interleukin-12 (IL-12).(More)
The genetic background of T lymphocytes influences development of the T helper (TH) phenotype, resulting in either resistance or susceptibility of certain mouse strains to pathogens such as Leishmania major. With an in vitro model system, a difference in maintenance of responsiveness of T cells to interleukin-12 (IL-12) was detected between BALB/c and(More)
A host's ability to resist certain pathogens such as Leishmania major can depend upon the phenotype of T helper (Th) subset that develops. Different murine genetic backgrounds are known to significantly alter the direction of Th subset development, although the cellular basis of this influence is poorly understood. To examine the basis of this effect we(More)
We have previously shown that dendritic cells isolated after overnight culture, which can express B7 and are potent stimulators of naive T cell proliferation, are relatively poor at inducing the proliferation of a panel of murine T helper 1 (Th1) clones. Maximal stimulation of Th1 clones was achieved using unseparated splenic antigen presenting cells (APC).(More)
This paper presents a new linguistic mechanism for expressing and controlling inter-process interactions. Unlike existent designs such as monitor- or message-based mechanisms, which generally provides a set of relatively low-level primitives for users to implement various inter-process synchronization constraints, this mechanism provides a general(More)
Chest radiography, CT, and MR imaging were performed in a 3-year-old girl who had posterior mediastinal fibromatosis with transforaminal intraspinal and chest wall extension. Chest radiographs and CT scans showed a slow-growing, noncalcified but locally aggressive left paravertebral mass. The mass was slightly hyperintense relative to muscle on both(More)
1161 PERSPECTIVES evant antigen. These data suggest a model in which populations of tissue-specifi c T regs arise during thymic development and then accumulate within those peripheral tissues on the basis of antigen recognition (see the fi gure). As tumors develop, these preexist-ing tissue-resident T regs are recruited into and/or expanded within the tumor(More)
In this paper we provide, for the first time to our knowledge, the effective orientation of the SHG source in cultured cortical neuronal processes in vitro. This is done by the use of the polarization sensitive second harmonic generation (PSHG) imaging microscopy technique. By performing a pixel-level resolution analysis we found that the SHG dipole source(More)
Interprocess interactions in concurrent programs serve two major functions: conditional exclusion and scheduling. This article presents high-level techniques for specification of scheduling policies, and for proving the starvation-free property of scheduling policies after they are formally specified. Specification is based on a scheduler model that(More)
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