Chwanrow Karim Baban

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In recent years, a greater appreciation for the microbes inhabiting human body sites has emerged. In the female mammary gland, milk has been shown to contain bacterial species, ostensibly reaching the ducts from the skin. We decided to investigate whether there is a microbiome within the mammary tissue. Using 16S rRNA sequencing and culture, we analyzed(More)
The ability to track microbes in real time in vivo is of enormous value for preclinical investigations in infectious disease or gene therapy research. Bacteria present an attractive class of vector for cancer therapy, possessing a natural ability to grow preferentially within tumours following systemic administration. Bioluminescent Imaging (BLI) represents(More)
Anti-cancer therapy faces major challenges, particularly in terms of specificity of treatment. The ideal therapy would eradicate tumor cells selectively with minimum side effects on normal tissue. Gene or cell therapies have emerged as realistic prospects for the treatment of cancer, and involve the delivery of genetic information to a tumor to facilitate(More)
This video describes the use of whole body bioluminesce imaging (BLI) for the study of bacterial trafficking in live mice, with an emphasis on the use of bacteria in gene and cell therapy for cancer. Bacteria present an attractive class of vector for cancer therapy, possessing a natural ability to grow preferentially within tumors following systemic(More)
Chylous ascites (chyloperitoneum) is a rare clinical condition, characterized by an accumulation of lymph fluid in the peritoneal cavity. Most commonly it is associated with abdominal malignancy (usually lymphoma). We present an unusual case of a woman who developed a persistent pseudocyst and recurrent chylous ascites following acute necrotizing(More)
1 of 2 DESCRIPTION A 78-year-old male presented with jaundice, fever, rigors and right upper quadrant pain. Ultrasound demonstrated gallbladder empyema and common bile duct (CBD) stones with mild CBD dilatation. Medical morbidity and prior partial gastrectomy precluded endoscopic treatment. Under ultrasound guidance an 8fr Navarre pigtail drain (Bard(More)
A 63-year-old man underwent endoscopic evaluation of the rectal stump for rectal bleeding and suffered a massive cerebral air embolism with severe neurological impairment and subsequent death. The patient underwent a Hartmann's procedure 9 month previously for ischaemic bowel and was noted to have portal hypertension at laparotomy. We hypothesise that air(More)
1 of 3 DESCRIPTION An 86-year-old woman presented with complete large bowel obstruction secondary to tumour ingrowth of a previously placed enteric stent ( fi gure 1 ). She was deemed not fi t for surgical intervention. A second stent (covered ultrafl ex stent) was inserted through the occluded baremetal stent using a combination of endoscopy and fl(More)
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