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C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling
- Pontus Boström, Nina M. Mann, +8 authors Bruce M. Spiegelman
- Cell
- 2010
The heart has the ability to grow in size in response to exercise, but little is known about the transcriptional mechanisms underlying physiological hypertrophy. Adult cardiomyocytes have also… (More)
- Xiaojun Liu, Junjie Xiao, +10 authors Anthony Rosenzweig
- Cell metabolism
- 2014
Exercise induces physiological cardiac growth and protects the heart against pathological remodeling. Recent work suggests exercise also enhances the heart's capacity for repair, which could be… (More)
- Chunyang Xiao, Marc Dymetman, Claire Gardent
- ACL
- 2016
We propose an approach for semantic parsing that uses a recurrent neural network to map a natural language question into a logical form representation of a KB query. Building on recent work by (Wang… (More)
- Marc Dymetman, Chunyang Xiao
- ArXiv
- 2016
We introduce LL-RNNs (Log-Linear RNNs), an extension of Recurrent Neural Networks that replaces the softmax output layer by a log-linear output layer, of which the softmax is a special case. This… (More)
Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling.
- Saumya Das, Takeshi Aiba, +14 authors Anthony Rosenzweig
- Circulation
- 2012
BACKGROUND
Heart failure is a growing cause of morbidity and mortality. Cardiac phosphatidylinositol 3-kinase signaling promotes cardiomyocyte survival and function, but it is paradoxically activated… (More)
- Kyu-Tae Kang, Matthew P. Coggins, Chunyang Xiao, Anthony Rosenzweig, J. Elaine Bischoff
- Angiogenesis
- 2013
Cell-based therapies to restore heart function after infarction have been tested in pre-clinical models and clinical trials with mixed results, and will likely require both contractile cells and a… (More)
- Vassilios J Bezzerides, Colin Platt, +7 authors Anthony Rosenzweig
- JCI insight
- 2016
The mechanisms by which exercise mediates its multiple cardiac benefits are only partly understood. Prior comprehensive analyses of the cardiac transcriptional components and microRNAs dynamically… (More)
- Jiahong Xu, Jiangmin Zhao, Graham Evan, Chunyang Xiao, Yan Cheng, Junjie Xiao
- Journal of Molecular Medicine
- 2011
MicroRNAs (miRNAs) are a novel class of small, non-coding, single-stranded RNAs that negatively regulate gene expression via translational inhibition or mRNA degradation followed by protein synthesis… (More)
- Chunyang Xiao, Marc Dymetman, Claire Gardent
- IJCAI
- 2017
Seq2seq models based on Recurrent Neural Networks (RNNs) have recently received a lot of attention in the domain of Semantic Parsing for Question Answering. While in principle they can be trained… (More)
- Ravi Vikram Shah, Jian Rong, +14 authors Jane E. Freedman
- JAMA cardiology
- 2018
Importance
Mortality is high among patients heart failure (HF) who are receiving treatment, and therefore identifying new pathways rooted in preclinical cardiac remodeling phenotypes may afford novel… (More)