Chunyang Liu

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Influential spreaders identification in social networks contributes to optimize the use of available resources and ensure the more efficient spread of information. In contrast to common belief that highly connected or core located users are most crucial spreaders, this paper shows that both user’s local and global structural properties matter in information(More)
Activation of NF-κB contributes to cardiac hypertrophy and the interleukin-1 receptor (IL-1R)-mediated MyD88-dependent signaling pathway predominately activates NF-κB. Recent studies have shown that the TIR/BB-Loop mimetic (AS-1) disrupted the interaction of MyD88 with the IL-1R, resulting in blunting of NF-κB activation. We have examined the effects of(More)
OBJECTIVE Plasma fibrinogen has been defined as a risk factor of cardiovascular disease and may play a role in the development of cardiac hypertrophy. We have previously demonstrated that the Toll-like receptor 4 (TLR4)-mediated myeloid differentiation primary response protein 88 (MyD88)-dependent nuclear factor-kappaB (NF-kappaB) pathway is involved in(More)
BACKGROUND Directly comparing gene expression profiles of estrogen receptor-positive (ER+) and estrogen receptor-negative (ER-) breast cancers cannot determine whether differentially expressed genes between these two subtypes result from dysregulated expression in ER+ cancer or ER- cancer versus normal controls, and thus would miss critical information for(More)
BACKGROUND Cancer cells typically exhibit large-scale aberrant methylation of gene promoters. Some of the genes with promoter methylation alterations play "driver" roles in tumorigenesis, whereas others are only "passengers". RESULTS Based on the assumption that promoter methylation alteration of a driver gene may lead to expression alternation of a set(More)
Real world Web mining applications usually have different requirements, such as massive data processing, low system latency, and high scalability. In order to meet these different requirements, we proposed a distributed text mining system with a layered architecture that divides the system functions into three layers, namely, the crawling and storage layer,(More)
1Jiangsu Provincial Key Laboratory of E-Business, Nanjing University of Finance and Economics, Nanjing 210003, China 2College of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, China 3Department of Information Systems, School of Economics and Management, Beihang University, Beijing 100191, China 4National(More)
The similarities and differences of eight vegetable oils produced in China were investigated in terms of their fatty acid, sterol, and tocopherol compositions and subsequent data processing by hierarchical clustering analysis and principal component analysis. The lipid profiles, acquired by analytical techniques tailored to each lipid class, revealed great(More)