Chunjuan Mi

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Exercise training lowers blood pressure and is a recommended nonpharmacological strategy and useful adjunctive therapy for hypertensive patients. Studies demonstrate that physical activity attenuates progression of hypertension. However, underlying mechanisms remain elusive. Vascular insulin resistance and endothelial dysfunction plays a critical role in(More)
AIMS Endothelial dysfunction and hypertension is more common in individuals with diabetes than in the general population. This study was aimed to investigate the underlying mechanisms responsible for endothelial dysfunction of type 1 diabetic rats fed with high-salt diet. MAIN METHODS Type 1 diabetes (DM) was induced by intraperitoneal injection of(More)
Wenjuan Xing,* Youyou Li,* Haifeng Zhang,* Chunjuan Mi, Zuoxu Hou, Michael J. Quon, and Feng Gao Department of Physiology, The Fourth Military Medical University, Xi’an, China; Experiment Teaching Center, The Fourth Military Medical University, Xi’an, China; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine,(More)
BACKGROUND Hypertension leads to cardiac hypertrophy as an adaptive response to increased workload. While initial development of hypertrophy is compensatory when contractile function is maintained, persistent stress on heart leads to deteriorated cardiac function and onset of heart failure. Mitochondrial dysfunction develops in the failing heart; however,(More)
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