Lactate Utilization Is Regulated by the FadR-Type Regulator LldR in Pseudomonas aeruginosa
A motif with a hyphenated dyad symmetry (TGGTCTTACCA) was identified as essential for the binding of LldR to the upstream region of lldP by using site-directed mutagenesis and interfered with the DNA-binding activity of L-Lactate and D-lactate.
Effects of 4-nonylphenol on spermatogenesis and induction of testicular apoptosis through oxidative stress-related pathways.
Body mass index and risk of lung cancer: Systematic review and dose-response meta-analysis
Keeping normal-to-moderate BMI should be prescribed as an evidence-based lifestyle tip for LC prevention in smokers, as quantitative evidence that increasing BMI is a protective factor against LC is provided.
4-Nonylphenol induces apoptosis, autophagy and necrosis in Sertoli cells: Involvement of ROS-mediated AMPK/AKT-mTOR and JNK pathways.
4-Nonylphenol induces autophagy and attenuates mTOR-p70S6K/4EBP1 signaling by modulating AMPK activation in Sertoli cells.
Targeting the PDGF-B/PDGFR-β Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-ββ Signaling and Attenuate Liver Fibrosis
A new pharmacological effect of levornidazole: Inhibition of NLRP3 inflammasome activation.
4‐Nonylphenol induces disruption of spermatogenesis associated with oxidative stress‐related apoptosis by targeting p53‐Bcl‐2/Bax‐Fas/FasL signaling
Taken together, NP‐induced apoptosis, hormonal deficiencies, and depletion of fructose potentially impairs spermatogenesis and sperm function.
Roseotoxin B Improves Allergic Contact Dermatitis through a Unique Anti-Inflammatory Mechanism Involving Excessive Activation of Autophagy in Activated T Lymphocytes.
Efficient Production of 2-Oxobutyrate from 2-Hydroxybutyrate by Using Whole Cells of Pseudomonas stutzeri Strain SDM
Whole cells of Pseudomonas stutzeri SDM, containing NAD-independent lactate dehydrogenases, effectively converted 2-hydroxybutyrate into 2-oxobutyrate, an important intermediate in the chemical, drug, and food industries.