Chunhua Liu

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Glutamate receptor-mediated neurotoxicity is a major mechanism contributing to hypoxic-ischemic brain injury (HIBI). Memantine is a safe non-competitive NMDA receptor blocker characterized by its low affinity and fast unblocking kinetics. Topiramate is an AMPA/KA receptor blocker and use-dependent sodium channel blocker with several other neuroprotective(More)
—With ever-increasing concerns on energy issues, the development of renewable energy sources is becoming more and more attractive. This paper first reviews both the wind power and photovoltaic (PV) power generation techniques and their maximum-power-point tracking (MPPT) methods. Then, a new stand-alone wind–PV hybrid generation system is proposed for(More)
—A new permanent-magnet (PM) hybrid brushless (PMHB) machine is proposed and implemented as the integrated starter–generator (ISG) for hybrid electric vehicles (HEVs). It has the advantages of higher torque density than other PMHB machines and much wider speed range than other PM brushless machines. The key is to tune its dc-field winding current in such a(More)
Recently, social tag recommendation has gained more attention in web research, and many approaches were proposed, which can be classified into two types: rule-based and classification-based approaches. However, too much expert experience and manual work are needed in rule-based approaches, and its generalization is limited. Additionally , there are some(More)
The suppressor of zeste-12 protein (SUZ12), a core component of Polycomb repressive complex 2 (PRC2), is implicated in transcriptional silencing by generating di- and tri-methylation of lysine 27 on histone H3 (H3K27Me3). Although SUZ12 is known to be of great importance in several human cancer tumorigenesis, limited data are available on the expression(More)
The permanent-magnet hybrid brushless (PMHB) motor adopts both DC field windings and PMs for excitation. It not only offers effective online flux control, but also flexible brushless DC (BLDC) or brushless AC (BLAC) operations. The key of this paper is to investigate two remedial strategies for fault-tolerant operations of the PMHB motor drive under(More)
During the asymmetric division of Drosophila neuroblasts (NBs), the scaffold Miranda (Mira) coordinates the subcellular distribution of cell-fate determinants including Staufen (Stau) and segregates them into the ganglion mother cells (GMCs). Here we show the fifth double-stranded RNA (dsRNA)-binding domain (dsRBD5) of Stau is necessary and sufficient for(More)