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Phylogenetic analysis of global hepatitis E virus sequences: genetic diversity, subtypes and zoonosis
TLDR
In most areas where HEV genotypes 3 and 4 were characterised, sequences from both humans and animals were highly conserved, indicating they originated from the same infectious sources.
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Manipulation of the Porcine Epidemic Diarrhea Virus Genome Using Targeted RNA Recombination
TLDR
A reverse genetics system is established based on targeted RNA recombination that allows the modification of the 3′-end of the viral genome, which encodes the structural proteins and the accessory ORF3 protein and will allow the rational design and development of next generation PEDV vaccines.
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Cell Attachment Domains of the Porcine Epidemic Diarrhea Virus Spike Protein Are Key Targets of Neutralizing Antibodies
TLDR
To understand the antigenic landscape of the PEDV spike protein, monoclonal antibodies were developed against the spike protein's S1 receptor binding region and their epitopes, neutralizing activity, and cross-reactivity toward multiple P EDV strains were characterized.
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Prevalence and Genetic Characterization of Cryptosporidium in Yaks in Qinghai Province of China
TLDR
Cryptosporidium bovis was the most common species, followed by C. parvum and C. ryanae, and all three species were found in yaks ranging in age from <1 year, 1–2 years, to >2 years.
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Specific and Modular Binding Code for Cytosine Recognition in Pumilio/FBF (PUF) RNA-binding Domains*♦
Pumilio/fem-3 mRNA-binding factor (PUF) proteins possess a recognition code for bases A, U, and G, allowing designed RNA sequence specificity of their modular Pumilio (PUM) repeats. However,…
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HCV 6a Prevalence in Guangdong Province Had the Origin from Vietnam and Recent Dissemination to Other Regions of China: Phylogeographic Analyses
TLDR
With an origin from Vietnam, 6a has become a local epidemic in Guangdong Province, where an increasing prevalence has subsequently led to 6a spread to many other regions of China.
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Distribution of Cryptosporidium species in Tibetan sheep and yaks in Qinghai, China.
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Migration Patterns of Hepatitis C Virus in China Characterized for Five Major Subtypes Based on Samples from 411 Volunteer Blood Donors from 17 Provinces and Municipalities
TLDR
This is the first study in which the HCV isolates represented such a large portion of the country, and thus, the results should shed light on the current understanding of HCV molecular epidemiology.
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The genetic diversity and evolutionary history of hepatitis C virus in Vietnam.
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Rapid detection of porcine circovirus type 2 using a TaqMan-based real-time PCR
TLDR
A sensitive, specific assay for the detection and quantitation of PCV2, designed and synthesized specific primers and a probe in the open reading frame 2, had a wide dynamic range with excellent linearity and reliable reproducibility and did not cross-react with porcine circovirus type 1.
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