Chung K. Lee

Learn More
Soft-computing techniques are commonly used to detect medical phenomena and help with clinical diagnoses and treatment. In this work, we propose a design for a computerized sleep scoring method, which is based on a fuzzy classifier and a genetic algorithm (GA). We design the fuzzy classifier based on the GA using a single electroencephalogram (EEG) signal(More)
OBJECTIVE To evaluate the safety and efficacy of stereotactic radiosurgery (SRS) compared to fractionated stereotactic radiation therapy (FSRT) for meningiomas treated over a seven year period. METHODS AND MATERIALS Of the 53 patients (15 male and 38 female) with 63 meningiomas, 35 were treated with SRS and the 18 patients with tumors adjacent to critical(More)
Metformin, the most widely prescribed drug for treatment of type 2 diabetes, has been shown to exert significant anticancer effects. Hyperthermia has been known to kill cancer cells and enhance the efficacy of various anti-cancer drugs and radiotherapy. We investigated the combined effects of metformin and hyperthermia against MCF-7 and MDA-MB-231 human(More)
OBJECT The authors sought to evaluate and improve the geometrical accuracy of a 3-tesla magnetic resonance (MR) imaging unit used for Gamma Knife surgery (GKS). METHODS To evaluate the geometrical accuracy of a Siemens Magnetom Trio 3-tesla MR imaging unit, two phantoms were used. Both phantoms were imaged with computed tomography (CT), a 1.5-tesla MR(More)
OBJECTIVES Evidence has implicated a possible role of tumor mutation status on local control (LC) with radiotherapy. BRAF is a proto-oncogene that is mutated in approximately 50% of patients with melanoma. We sought to analyze the influence of BRAF status on LC of melanoma brain metastases (MBM) following Gamma Knife radiosurgery (GK). METHODS Among 125(More)
The late marginal heading date (LMHD) for normal maturation has been assessed to infer the range of late transplanting date and applicability of a new cropping system. A minimum threshold temperature for grain filling can be used to determine the late marginal heading date that would allow normal maturation. In this study, a statistical procedure was(More)
PURPOSE To examine radiation dose response for low-grade glioma (LGG) based on our institutional experience and to review the literature on this topic. METHODS AND MATERIALS Sixty-seven patients with supratentorial low-grade nonpilocytic astrocytomas (n=36) or oligodendrogliomas (n=31) were treated with postoperative radiation therapy (RT). Twenty-seven(More)
  • 1