Chung-Huei Hsu

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The cellular apoptosis susceptibility (CSE1L/CAS) protein is highly expressed in cancer, and its expression is positively correlated with high cancer stage, high cancer grade, and worse outcomes of patients. CSE1L (or CAS) regulates chemotherapeutic drug-induced cancer cell apoptosis and may play important roles in mediating the cytotoxicities of(More)
BACKGROUND Invasiveness and metastasis are the most common characteristics of non small cell lung cancer (NSCLC) and causes of tumour-related morbidity and mortality. Mitogen-activated protein kinases (MAPKs) signalling pathways have been shown to play critical roles in tumorigenesis. However, the precise pathological role(s) of mitogen-activated protein(More)
A 23-year-old female suffered from a locally invasive well-differentiated thyroid papillary carcinoma with cer-vical lymph nodes metastases and disseminated lung metastases 16 years ago (in 1989). After undergoing a surgical operation, she had received subsequent accumulated therapeutic dose of 13 GBq (350 mCi) of 131 I in the following two years.(More)
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a multiple-site, multiple-species carcinogen that induces cancer in multiple organs. The molecular mechanisms underlying TCDD-induced lung tumorigenesis remain unclear. In the present study, a two-stage lung tumorigenesis model was established by administrating a single low dose of(More)
OBJECTIVE The early identification of subjects at high risk for diabetes is essential, thus, random rather than fasting plasma glucose is more useful. We aim to evaluate the time interval between pre-diabetes to diabetes with anti-diabetic drugs by using HbA1C as a diagnostic tool, and predicting it using a mathematic model. METHODS We used the Taipei(More)
Malignant melanoma of the uterine cervix is a rare extracutaneous melanoma which develops aggressively and is associated with a bleak prognosis. To our knowledge, no prior published reports have discussed the role of 18F-FDG positron emission tomography/computed tomography (PET/CT) in managing this disease. Our case study involved a 66-year-old woman with a(More)
The frequency of double primary cancers synchronously found in an individual has been increasing. However, synchronous or asynchronous triple primary cancers have rarely been repor ted. A 69-year-old female received an operation for right breast cancer and subsequent chemotherapy in 2001. During the 5-year follow up period, second and third primary cancers(More)
Two cases of early breast cancer were incidentally detected by FDG-PET among 585 examiners in our hospital. One case was primary breast cancer in an asymptomatic individual and the other was second primary cancer in a patient with ovarian cancer. The size of each of the tumors was approximate 1 cm in diameter. The maximal standard uptake value of the(More)
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