Chung-Che Wu

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Mild traumatic brain injury (mTBI) is one of the most common neurological disorders. Most patients diagnosed with mTBI could fully recover, but 15% of patients suffer from persistent symptoms. In recent studies, genetic factors were found to be associated with recovery and clinical outcomes after TBI. In addition, results from our previous research have(More)
Refined radio-isotopic dating techniques have been applied to Orgnac 3, a Late Acheulean and Early Middle Palaeolithic site in France. Evidence of Levallois core technology appeared in level 4b in the middle of the sequence, became predominant in the upper horizons, and was best represented in uppermost level 1, making the site one of the oldest examples of(More)
The association between solar activity and Asian monsoon (AM) remains unclear. Here we evaluate the possible connection between them based on a precisely-dated, high-resolution speleothem oxygen isotope record from Dongge Cave, southwest China during the past 4.2 thousand years (ka). Without being adjusted chronologically to the solar signal, our record(More)
We refer to periods of subduction strain accumulation beneath the Mentawai Islands, Sumatra, as " supercycles, " because each culminates in a series of partial ruptures of the megathrust in its final decades. The finale of the previous supercycle comprised two giant earthquakes in 1797 and 1833 and whatever happened in between. This behavior between two(More)
The purpose of this study was to compare the effect of PbtO2-guided therapy with traditional intracranial pressure- (ICP-) guided treatment on the management of cerebral variables, therapeutic interventions, survival rates, and neurological outcomes of moderate and severe traumatic brain injury (TBI) patients. From 2009 to 2010, TBI patients with a Glasgow(More)
BACKGROUND AND AIM Mild traumatic brain injury (mTBI) causes transient sleep disorders and circadian dysrhythmia. One of the clock genes, PERIOD3 (PER3), regulates the circadian rhythm and contains a genetic polymorphism, namely a variable-number tandem repeat in the coding area with either four or five repeats. PER3(5) carriers are inclined to have a(More)
Monumental tombs within ancient civilizations worldwide hold precious clues for deciphering the architectural skill, acumen, and industry of prehistoric cultures. Most tombs were constructed from abiotic materials-stone, soil, and/or clay, predominately-and were built to permanently inter royalty or high-status individuals. On the island of Kosrae in the(More)
Histories of vertical crustal motions at convergent margins offer fundamental insights into the relationship between interplate slip and permanent deformation. Moreover, past abrupt motions are proxies for potential tsunamigenic earthquakes and benefit hazard assessment. Well-dated records are required to understand the relationship between past earthquakes(More)
Modern acidification by the uptake of anthropogenic CO2 can profoundly affect the physiology of marine organisms and the structure of ocean ecosystems. Centennial-scale global and regional influences of anthropogenic CO2 remain largely unknown due to limited instrumental pH records. Here we present coral boron isotope-inferred pH records for two periods(More)
BACKGROUND Instead of surgical intervention, endovascular treatment with GDC has become an important tool to treat intracranial aneurysm in recent years. However, intraoperative aneurysm rupture remains a devastating complication for physicians. Rapid and precise packing with coils and external ventricular drainage are advised. Stereotactic aspiration of an(More)
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