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  • Influence
Tobacco smoking in China: Prevalence, disease burden, challenges and future strategies
About one‐third of the world's tobacco is produced and consumed in China. Despite existing tobacco control policies and activities, the prevalence of smoking in China remains high with 350 millionExpand
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Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial.
BACKGROUND Increased oxidative stress and inflammation has a role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Drugs with antioxidant and anti-inflammatory properties, such asExpand
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Expert consensus on acute exacerbation of chronic obstructive pulmonary disease in the People’s Republic of China
  • B. Cai, S. Cai, +22 authors C. Bai
  • Medicine
  • International journal of chronic obstructive…
  • 25 April 2014
Chronic obstructive pulmonary disease (COPD) is a common disease that severely threatens human health. Acute exacerbation of COPD (AECOPD) is a major cause of disease progression and death, andExpand
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  • Open Access
FoxM1 mediated resistance to gefitinib in non-smallcell lung cancer cells
Aim:Gefitinib is effective in only approximately 20% of patients with non-small-cell lung cancer (NSCLC), and the underlying mechanism remains unclear. FoxM1 is upregulated in NSCLC and associatedExpand
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  • Open Access
Effect of noninvasive positive pressure ventilation on weaning success in patients receiving invasive mechanical ventilation: a meta‐analysis
Background Noninvasive positive pressure ventilation (NIPPV) has been proposed to shorten the duration of mechanical ventilation in intubated patients, especially those who fail initial weaning fromExpand
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Deletion of aquaporin 5 aggravates acute lung injury induced by Pseudomonas aeruginosa.
BACKGROUND Aquaporin (AQP) is a membrane protein that facilitates osmotic water transport. Aquaporin 5 (AQP5) expresses at type I alveolar epithelia of apical membrane that confers high osmotic waterExpand
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Two microRNA panels to discriminate three subtypes of lung carcinoma in bronchial brushing specimens.
  • W. Huang, J. Hu, +11 authors S. Lu
  • Medicine
  • American journal of respiratory and critical care…
  • 1 December 2012
RATIONALE Effective treatment for lung cancer requires accuracy in subclassification of carcinoma subtypes. OBJECTIVES To identify microRNAs in bronchial brushing specimens for discriminating smallExpand
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Comparison of clinical features between non-smokers with COPD and smokers with COPD: a retrospective observational study
Background Smoking is a major risk factor for chronic obstructive pulmonary disease (COPD); however, the similarities and differences in clinical presentation between smokers and nonsmokers are notExpand
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  • Open Access
MIOTIC study: a prospective, multicenter, randomized study to evaluate the long-term efficacy of mobile phone-based Internet of Things in the management of patients with stable COPD
Chronic obstructive pulmonary disease (COPD) is a common disease that leads to huge economic and social burden. Efficient and effective management of stable COPD is essential to improve quality ofExpand
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  • Open Access
Prevention and management of lung cancer in China
Lung cancer is the leading cause of cancer‐related death worldwide. In China, the incidence of lung cancer has grown rapidly, resulting in a large social and economic burden. Several researchers haveExpand
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