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The ubiquitin-proteasome (Ub-Pr) degradation pathway regulates many cellular activities, but how ubiquitinated substrates are targeted to the proteasome is not understood. We have shown previously that valosin-containing protein (VCP) physically and functionally targets the ubiquitinated nuclear factor kappaB inhibitor, IkappaBalpha to the proteasome for(More)
The inactivation of the prototype NF-kappaB inhibitor, IkappaBalpha, occurs through a series of ordered processes including phosphorylation, ubiquitin conjugation, and proteasome-mediated degradation. We identify valosin-containing protein (VCP), an AAA (ATPases associated with a variety of cellular activities) family member, that co-precipitates with(More)
The cell carbohydrate content of cyanobacteria can alter buoyancy, and the ability to regulate the buoyancy is one of the most important mechanisms of cyanobacterial blooms. The net accumulation of carbohydrate in cell is affected by photosynthesis, respiration, synthesis of proteins, and other metabolisms, which are connected to the growth. The aim of this(More)
0950-7051/$ see front matter 2012 Elsevier B.V. A http://dx.doi.org/10.1016/j.knosys.2012.08.015 ⇑ Corresponding author. Tel.: +86 15811424568; fa E-mail address: guosen324@163.com (S. Guo). Accurate annual power load forecasting can provide reliable guidance for power grid operation and power construction planning, which is also important for the(More)
Interactions of Neotyphodium gansuense, Achnatherum inebrians, and nine fungal pathogens were studied by tests of inhibition of four fungal pathogens by Neotyphodium endophytes in vitro and by inoculation of nine fungal pathogens on detached leaves of endophyte-infected (E+) and endophyte-free (E-) plants. Compared with the controls, most isolates of N.(More)
The genetic elements and regulatory mechanisms responsible for human interleukin 9 (IL-9) gene expression in a human T cell leukemia virus type I-transformed human T cell line, C5MJ2, were investigated. We demonstrated that IL-9 gene expression is controlled, at least in part, by transcriptional activation. Transient expression of the luciferase reporter(More)
The ubiquitin-dependent proteasome-mediated (Ub-Pr) degradation pathway has been shown to regulate a large variety of substrates, including nuclear, cytosolic, and membrane proteins. In mammalian systems, polyubiquitin modification has been identified in a number of cell surface receptors for more than a decade; however, its biological significance has(More)
Rasheed rat sarcoma virus (RaSV) has been shown to code for a protein of 29,000 Mr not present in replication-competent rat type C helper virus (RaLV)-infected cells. This protein is a fused gene product consisting of a portion of the RaLV p15 gag protein and the transformation-specific 21,000 Mr (p21) ras protein, which is also found in Harvey murine(More)
Plant diversity in experimental systems often enhances ecosystem productivity, but the mechanisms causing this overyielding are only partly understood. Intercropping faba beans (Vicia faba L.) and maize (Zea mays L.) result in overyielding and also, enhanced nodulation by faba beans. By using permeable and impermeable root barriers in a 2-y field(More)
OBJECTIVE To determine the current status and influence factors of reporting quality of the Chinese meta-analysis on stomatology. METHODS A comprehensive electronic search was carried out through Chinese BioMedical Literature Database (CBM), VIP Database for Chinese Technical Periodicals (VIP) and China National Knowledge Infrastructure (CNKI) and a hand(More)