Chun Zheng

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The increasing incidence of invasive fungal infections (IFI) in immunocompromised patients emphasizes the need to improve diagnostic tools. We established a DNA microarray to detect and identify DNA from 14 fungal pathogens (Aspergillus fumigatus, Aspergillus flavus, Aspergillus terreus, Candida albicans, Candida dubliniensis, Candida glabrata, Candida(More)
The detection and identification of retroviral transcripts in brain samples, cerebrospinal fluid, and plasma of individuals with recent-onset schizophrenia and schizoaffective disorders suggest that activation or upregulation of distinct human endogenous retroviruses (HERVs) may play a role in the etiopathogenesis of neuropsychiatric diseases. To test this(More)
Conditioned place avoidance (CPA) paradigm has been used to investigate the affective component of pain. Although the anterior cingulate cortex (ACC) has been demonstrated to play an important role in the affective aspect of pain, whether the other prefrontal subdivisions are involved in pain-related aversion is unknown. The present study investigated the(More)
OBJECTIVE To analyze the immunological pattern of nasal polyposis in patients with and without allergy, the percentages of CD4+ cells expressing intracellular interferon-gamma and interleukin-4 (T helper [T(H)] type 1 and 2 cells) were measured by flow cytometry in samples from patients with nasal polyps. METHODS Samples from 32 patients (16 atopic, 16(More)
—The characteristics of embedded systems is analyzed in detail, embedded software testing technology is introduced in host and target testing, a comprehensive embedded software testing process model is put forward with the shortcomings of software testing V-model. Software testing is imported in the stage of requirement, and the performance of the(More)
Centrosomes play fundamental roles in mitotic spindle organisation, chromosome segregation and maintenance of genetic stability. Recently, we have demonstrated that the tyrosine kinase inhibitor imatinib induces centrosome and chromosome aberrations in vitro. Here, we comparatively investigated the effects of imatinib and the more potent successor drug(More)
BACKGROUND The aim of this study was to investigate the expression of MUC5AC and MUC5B messenger RNAs (mRNAs) and localization of these proteins in human sinus mucosa of chronic rhinosinusitis (CRS) and CRS with nasal polyposis (CRS/NP). METHODS Maxillary sinus ostia mucosa was harvested from patients undergoing endoscopic sinus surgery for CRS, CRS/NP,(More)
The three-center hydrogen bond in diaryl amide 1 was examined by IR and 1H NMR spectroscopy, X-ray crystallography, and ab initio calculations. By comparing 1 with its structural isomers 2, 3 and 4, and with its conformational isomers 1a-c, it was found that the two two-center components of the three-center interaction reinforce each other, that is, the(More)
OBJECTIVES To investigate the expression of epidermal growth factor receptor (EGFR) messenger RNA (mRNA) in human sinus mucosa and to compare the expression of EGFR and EGF among patients with chronic rhinosinusitis (CRS), patients with CRS and nasal polyposis (CRS/NP), and a healthy control group. DESIGN Maxillary sinus ostia mucosa was harvested from(More)
A testing strategy was proposed to deal with the parallelism of unit testing based on the priority of function. The influence of parameters, global and local variables on the proper realization of the control flow of function was analyzed in this paper. The quantitive mathematical model of the weight influencing factor was built, and a directed acycline(More)