Ten-Eleven Translocation (Tet) family of dioxygenases dynamically regulates DNA methylation and has been implicated in cell lineage differentiation and oncogenesis. Yet their functions and mechanisms of action in gene regulation and embryonic development are largely unknown. Here, we report that Xenopus Tet3 plays an essential role in early eye and neural… (More)
Liver X receptor (LXR) nuclear receptors regulate the expression of genes involved in whole body cholesterol trafficking, including absorption, excretion, catabolism, and cellular efflux, and possess both anti-inflammatory and antidiabetic actions. Accordingly, LXR is considered an appealing drug target for multiple indications. Synthetic LXR agonists… (More)
Organolead halide perovskites have attracted substantial attention because of their excellent physical properties, which enable them to serve as the active material in emerging hybrid solid-state solar cells. Here we investigate the phototransistors based on hybrid perovskite films and provide direct evidence for their superior carrier transport property… (More)
We propose a model for jointly predicting stock price and volume at the tick-by-tick level. We model the investors' preferences by a random utility model that incorporates several important behavioral biases such as the status quo bias, the disposition effect, and loss-aversion. Our model is a logistic regression model with incomplete information;… (More)
In this study, the effects of both transient and long-term inorganic carbon (IC) addition on the anaerobic ammonium oxidation (ANAMMOX) process under pseudo-steady-state and substrate inhibitions were analyzed using reactor performance and measures of sludge activity. Compared with the nitrogen removal rate (NRR) of 3.42 kg N m−3 day−1 in the control… (More)
This paper considers an SEIT epidemic model that incorporates proportion recruitment and with vertical transmission. By means of Lyapunov function and LaSalle s invariant set theorem, we proved the global asymptotical stable results of the disease-free equilibrium and the en-demic equilibrium with the help of numerical simulations.