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Past efforts to improve plant tolerance to osmotic stress have had limited success owing to the genetic complexity of stress responses. The first step towards cataloging and categorizing genetically complex abotic stress responses is the rapid discovery of genes by the large-scale partial sequencing of randomly selected cDNA clones or expressed sequence(More)
Ten-Eleven Translocation (Tet) family of dioxygenases dynamically regulates DNA methylation and has been implicated in cell lineage differentiation and oncogenesis. Yet their functions and mechanisms of action in gene regulation and embryonic development are largely unknown. Here, we report that Xenopus Tet3 plays an essential role in early eye and neural(More)
The synaptic mechanisms underlying excitation in the rat's central nucleus of the inferior colliculus (ICC) were examined by making whole-cell patch clamp recordings in brain slice preparations of the auditory midbrain. Responses were elicited by current pulse stimulation of the lateral lemniscus and recordings were made in ICC using either current clamp or(More)
Whole-cell patch clamp recordings were made from neurons in a brain slice preparation of the inferior colliculus in 11-15-day-old rat pups. Synaptic responses were elicited by applying a current pulse to the lateral lemniscus just below the central nucleus of the inferior colliculus. To examine GABAergic inhibition in the inferior colliculus all excitatory(More)
The central nucleus of the inferior colliculus (ICC) is a major site of synaptic interaction in the central auditory system. To understand how ICC neurons integrate excitatory and inhibitory inputs for processing temporal information, we examined postsynaptic responses of ICC neurons to repetitive stimulation of the lateral lemniscus at 10-100 Hz in rat(More)
Liver X receptor (LXR) nuclear receptors regulate the expression of genes involved in whole body cholesterol trafficking, including absorption, excretion, catabolism, and cellular efflux, and possess both anti-inflammatory and antidiabetic actions. Accordingly, LXR is considered an appealing drug target for multiple indications. Synthetic LXR agonists(More)
The feasibility of anaerobic ammonium oxidation (ANAMMOX) process to treat wastewaters containing sulfide was studied in this work. Serum bottles were used as experimental containers in batch tests to analyze the short-term response of the ANAMMOX process under sulfide stress. The IC(50) of sulfide-S for ANAMMOX biomass was substrates-dependent and was(More)
Whole-cell patch clamp recordings were made from neurons in the central nucleus of the inferior colliculus (ICC) in brain slices from rat (8-13 days old). ICC neurons were classified by their discharge pattern in response to depolarizing and hyperpolarizing current injection. Excitatory postsynaptic currents (EPSCs) were elicited by stimulation of synaptic(More)
Histone lysine acetylation has emerged as a key regulator of genome organization. However, with a few exceptions, the contribution of each acetylated lysine to cellular functions is not well understood because of the limited specificity of most histone acetyltransferases and histone deacetylases. Here we show that the Mst2 complex in Schizosaccharomyces(More)
The effect of salinity shock (5-60 g l(-1) NaCl) on anaerobic ammonium oxidation (Anammox) process performance was investigated. The response to the shock loads can be divided into three stages: a sensitive period, an interim stable period and a recovery period which lasted 6-26 d. When exposed to NaCl shocks for 12h, the sludge retention time (SRT) of the(More)