• Publications
  • Influence
Long noncoding RNA expression profiles of the doxorubicin-resistant human osteosarcoma cell line MG63/DXR and its parental cell line MG63 as ascertained by microarray analysis.
TLDR
It is found that lncRNA ENST00000563280 was distinctly increased in specimens of OS patients with a poor chemoresponse compared to those with a good chemoreSponse and the patients of lower expression of it may survive longer than those of higher expression, which suggest that it may serve as a biomarker to predict the chemore Sponse and prognosis of osteosarcoma patients.
Antisense lncRNA FOXC2-AS1 promotes doxorubicin resistance in osteosarcoma by increasing the expression of FOXC2.
TLDR
It is concluded that the lncRNA FoxC2-AS1 may promote doxorubicin resistance in OS by increasing the expression of transcription factor FOXC2, further facilitating ABCB1 expression.
A long non-coding RNA contributes to doxorubicin resistance of osteosarcoma
TLDR
It is concluded that lncRNA ODRUL may act as a pro-doxorubicin-resistant molecule through inducing the expression of the classical multidrug resistance-related ABCB1 gene in osteosarcoma cells .
Custom-made intercalary endoprosthetic reconstruction for a parosteal osteosarcoma of the femoral diaphysis: A case report.
TLDR
A 44-year-old female patient who presented with a palpable mass of the left thigh was diagnosed with parosteal osteosarcoma, and a long diaphyseal segment of the femur containing the tumor was resected along with a healthy margin of soft tissues.
Reconstruction of lateral knee joint stability following resection of proximal fibula tumors
TLDR
Reconstruction of the LCL and biceps femoris tendon to the lateral tibial metaphysis with a suture anchor was a safe, reliable and simple technique following resection of proximal fibula tumors.
Analyzing the Interactions of mRNAs and ncRNAs to Predict Competing Endogenous RNA Networks in Osteosarcoma Chemo-Resistance.
TLDR
These findings may provide new evidence for the underlying mechanism of OS chemo-resistance and uncover some novel targets for reversing it.
LncRNA ODRUL Contributes to Osteosarcoma Progression through the miR-3182/MMP2 Axis.
TLDR
It is shown that ODRUL is upregulated in OS tissues and cell lines and correlates with poor prognosis, and may provide a new target in OS therapy.
Enhanced chemosensitivity of drug-resistant osteosarcoma cells by lentivirus-mediated Bcl-2 silencing.
TLDR
Investigation of whether the inhibition of Bcl-2 by lentivirus-mediated RNA interference would enhance doxorubicin cytotoxicity in the drug-resistant human osteosarcoma MG63 cells revealed that B cl-2 knock-down increased cellular apoptosis and the MG 63 cells became sensitive to doxorbicin.
Surgical Anatomy of the Radial Nerve at the Elbow and in the Forearm: Anatomical Basis for Intraplexus Nerve Transfer to Reconstruct Thumb and Finger Extension in C7 - T1 Brachial Plexus Palsy.
TLDR
Branches to the brachioradialis, extensor carpi radialis longus, and supinator can be transferred to the posterior interosseous nerve to restore hand movement in patients with C7 - T1 brachial plexus palsies; the supinator branch is probably the best choice in this regard.
p21WAF1/CIP1 gene DNA sequencing and its expression in human osteosarcoma.
TLDR
Along with the increase of malignancy, the expression of p21WAF1/CIP1mRNA and P21 protein in osteosarcoma tends to decrease, which can provide a basis for further research.
...
1
2
3
...