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Tumor hypoxia is associated with disease progression and treatment failure, but the hypoxia signaling mechanism is not fully understood. Here, we show that KLHL20, a Cullin3 (Cul3) substrate adaptor induced by HIF-1, coordinates with the actions of CDK1/2 and Pin1 to mediate hypoxia-induced PML proteasomal degradation. Furthermore, this PML destruction(More)
This paper presents a novel error concealment algorithm for H.264/AVC, which is constructed according to the spatial relationship of motion vectors between corrupted macroblocks and neighboring received macroblocks. We model the motion field such that the lost pixel is a function of all MVs of the neighboring MVs. We compare our method against a(More)
This paper proposes a simple and effective built-in self-repair (BISR) scheme for content addressable memories (CAMs) with address-input-free writing function. A pro-grammable built-in self-test (BIST) circuit is designed to generate different March-like test algorithms which can cover typical random access memory faults and comparison faults. A(More)
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