Chun-Kai Chang

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We describe the clinical course and virological characteristics of the first H7N9 influenza case in a Taiwanese patient; this patient had detectable viruses in the airway for 2 weeks, during which time an oseltamivir resistance-associated R292K mutation rapidly emerged. Anti-H7N9 antibody was detected 21 days after onset of symptoms, when H7N9 viral load(More)
PURPOSE To report on 1-year visual, anatomical, and angiographic responses with intravitreal bevacizumab for the treatment of polypoidal choroidal vasculopathy. METHODS Patients with macula-involved, symptomatic polypoidal choroidal vasculopathy with initial best-corrected visual acuity of 20/400 or better and a minimal follow-up period of 12 months were(More)
This study extended the computation of GLCM (gray level co-occurrence matrix) to a three-dimensional form. The objective was to treat hyperspectral image cubes as volumetric data sets and use the developed 3D GLCM computation algorithm to extract discriminant volumetric texture features for classification. As the kernel size of the moving box is the most(More)
Anti-N-methyl-d-aspartate (anti-NMDA) receptor encephalitis is a newly recognized, potentially fatal, but treatable autoimmune disease. Good outcome predictors include milder severity of symptoms, no need for intensive care unit admission, early aggressive immunotherapy, and prompt tumor removal. We report a case of a young girl aged 3 years 2 months and(More)
PURPOSE To compare the efficacy and the detrimental effects of half-drug dose and half-laser light fluence of photodynamic therapy (PDT) for the treatment of chronic central serous chorioretinopathy. DESIGN We conducted a prospective randomized, observer-masked comparison study. METHODS Forty eyes (40 patients) with chronic central serous(More)
Because of antibiotic abuse in human and animal populations, normal intestinal microflora such as enterococci have emerged as important nosocomial pathogens. We describe a community-acquired case of multiresistant Enterococcus faecalis corneal ulcer because of a cat scratch, and review previous enterococcal isolations from cornea. A 23-year-old woman was(More)
Existing multi-robot cooperative perception solutions can be mainly classified into two categories, measurement-based and belief-based, according to the information shared among robots. With well-controlled communication, measurement-based approaches are expected to achieve theoretically optimal estimates while belief-based approaches are not because the(More)
In this paper, an integrated water turbidity detection<sup>&#x2020;</sup>. method on dam gate is proposed. Based on multi-spectral image analysis and the transmitted power analysis of immersed optical fiber, the quality of water used for waterpower generator can be inspected automatically thus to protect the power generator from damage due to silt.(More)
Vibrio vulnificus can cause severe skin and soft tissue infection (SSTI). The pathogen is an opportunistic marine bacterium that is likely to infect patients with chronic liver disease, patients in an immunocompromised state, and those in end-stage renal disease. V. vulnificus gains entry through soft tissues by direct penetration of a wound by infected(More)