Learn More
BACKGROUNDS MicroRNAs are small noncoding RNAs involved in posttranscriptional gene regulation, which play an important role in both physiological functioning and pathological progression. The miR-221/miR-222 microRNA family has been shown to be related to the neoplastic process in a number of different types of cancers; nevertheless, its function in oral(More)
Hepcidin is one of the regulators of iron metabolism. The expression of hepcidin is induced in spleens and livers of mice infected with pathogenic bacteria. Recent studies have indicated that serum hepcidin level is also increased in human subjects infected with Plasmodium falciparum. The mechanism of the regulation of hepcidin expression and its role in(More)
This study estimated the risk of developing psychotic disorders by comparing children with ADHD to non-ADHD controls, and to examine whether methylphenidate (MPH) treatment influences the risks of psychotic disorders. A nationwide cohort of patients who were newly diagnosed with ADHD (n=73,049) and age- and gender-matched controls (n=73,049) were selected(More)
OBJECTIVE The purpose of this study is to determine the risk of developing depressive disorders by evaluating children with attention-deficit/hyperactivity disorder (ADHD) in comparison to controls that do not have ADHD, as well as to analyze whether the medications used to treat ADHD, methylphenidate (MPH) and atomoxetine (ATX), influence the risk of(More)
PURPOSE This study explores trends in attention-deficit/hyperactivity disorder (ADHD) medications in Taiwan from 2000 to 2011 and whether negative media coverage of Ritalin in January 2010 impacted ADHD prescriptions throughout the country. METHOD Patients throughout Taiwan who had been newly diagnosed with ADHD (n = 145,269) between January 2000 and(More)
Peak-to-average power ratio (PAPR) reduction methods for orthogonal frequency division multiplexing (OFDM) systems commonly use four times oversampling for the discrete-time OFDM signal to approximate the peak of the continuous-time OFDM signal. However, the four times oversampling process increases the computational complexity. In this paper, we propose a(More)
Functional rectification in late design stages has been a crucial process in modern complex system design. This paper proposes a robust functional ECO engine, which applies SAT proof minimization and interpolation techniques to automate patch construction to make old implementation and golden specification functionally equivalent. The SAT proof minimization(More)
Constrained random simulation is becoming the mainstream methodology in functional verification. In order to achieve the verification closure, a high-throughput and evenly-distributed constrained random pattern generator has become a must. In this paper, we propose a novel Range-Splitting heuristic and a Solution-Density Estimation technique (RSSDE) to(More)
Constrained random simulation is becoming the mainstream methodology to verify system-wide properties in functional verification. It is a must to develop a high-throughput constrained random pattern generator, which is able to support arbitrary distribution. In this paper, we propose a novel range-splitting heuristic and a solution-density estimation(More)