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- Publications
- Influence
DeSUMOylation: An Important Therapeutic Target and Protein Regulatory Event.
- Chun-Jie Huang, D. Wu, F. Khan, Lijun Huo
- Biology, Medicine
- DNA and cell biology
- 6 November 2015
The discovery of the process of small ubiquitin-like modifier (SUMO)-mediated post-translational modification of targets (SUMOylation) in early 1990s proved to be a significant step ahead in… Expand
Novel Attributions of TREMs in Immunity.
- N. S. Pandupuspitasari, F. Khan, Chun-Jie Huang, X. Chen, S. Zhang
- Biology, Medicine
- Current issues in molecular biology
- 2016
The emerging role of the TREMs (Triggering Receptors Expressed by Myeloid cells) family in inflammation makes it important to explore their molecular mechanisms governing key pathways in inflammatory… Expand
The SUMO Protease SENP3 Orchestrates G2-M Transition and Spindle Assembly in Mouse Oocytes
- Chun-Jie Huang, D. Wu, F. Khan, Lijun Huo
- Biology, Medicine
- Scientific reports
- 23 October 2015
Oocyte meiosis is a transcription quiescence process and the cell-cycle progression is coordinated by multiple post-translational modifications, including SUMOylation. SENP3 an important… Expand
Bisphenol AF negatively affects oocyte maturation of mouse in vitro through increasing oxidative stress and DNA damage.
- Zhi-Ming Ding, Xiaofei Jiao, +7 authors Lijun Huo
- Biology, Medicine
- Chemico-biological interactions
- 25 December 2017
Bisphenol AF (BPAF) is commonly used in industry production as a substitute for Bisphenol A (BPA). Many studies showed that BPAF negatively affect some physiological processes in humans and animals.… Expand
Maternal SENP7 programs meiosis architecture and embryo survival in mouse.
- Chun-Jie Huang, D. Wu, +6 authors Lijun Huo
- Biology, Medicine
- Biochimica et biophysica acta. Molecular cell…
- 1 July 2017
Understanding the mechanisms underlying abnormal egg production and pregnancy loss is significant for human fertility. SENP7, a SUMO poly-chain editing enzyme, has been regarded as a mitotic… Expand
SUMOylation: A link to future therapeutics.
- F. Khan, N. S. Pandupuspitasari, Chun-Jie Huang, Xingjie Hao, S. Zhang
- Biology, Medicine
- Current issues in molecular biology
- 4 January 2016
SUMOylation, much of a similar process like ubiquitination catches attention across various research groups as a potential therapeutic target to fight various infectious and cancerous diseases. This… Expand
Abce1 orchestrates M-phase entry and cytoskeleton architecture in mouse oocyte
- Xiaofei Jiao, Chun-Jie Huang, +5 authors Lijun Huo
- Biology, Medicine
- Oncotarget
- 24 March 2017
ATP-binding cassette E1 (ABCE1) is a member of the ATP-binding cassette transporters and essential for diverse biological events regulating abroad range of biological functions including viral… Expand
Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells
- D. Wu, Chun-Jie Huang, +6 authors Lijun Huo
- Biology, Medicine
- Oncotarget
- 16 August 2017
Sertoli cells, by creating an immune-privileged and nutrition supporting environment, maintain mammalian spermatogenesis and thereby holds the heart of male fertility. Olaquindox, an effective feed… Expand
SENP3 grants tight junction integrity and cytoskeleton architecture in mouse Sertoli cells.
- D. Wu, Chun-Jie Huang, +5 authors Lijun Huo
- Biology, Medicine
- Oncotarget
- 7 April 2017
Germ cells develop in a sophisticated immune privileged microenvironment provided by specialized junctions contiguous the basement membrane of the adjacent Sertoli cells that constituted the… Expand
Expression, Localization of SUMO-1, and Analyses of Potential SUMOylated Proteins in Bubalus bubalis Spermatozoa
- R. D. Brohi, L. Wang, +7 authors Lijun Huo
- Biology, Medicine
- Front. Physiol.
- 13 June 2017
Mature spermatozoa have highly condensed DNA that is essentially silent both transcriptionally and translationally. Therefore, post translational modifications are very important for regulating sperm… Expand