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Keywords: Genetic algorithm Knowledge discovery Machine learning Defense Maritime security Decision support a b s t r a c t Due to the large volume of data related to vessels, to manually pore through and to analyze the information in a bid to identify potential maritime threat is tedious, if at all possible. This study aims to enhance maritime situational(More)
The importance of customer requirement management in product development has been well recognized in both academia and industries alike. This paper provides a comprehensive review of the state-of-the-art research in this field. Customer requirement management entails various issues related to requirement elicitation, analysis and specification, as well as(More)
Areca (betel) was recently proved a carcinogenic substance by the International Agency for Research on Cancer. However, the signaling impact of areca in oral keratinocyte is still obscure. Mitogen-activated protein kinase superfamilies, including extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinases (JNK) and p38, together with transcription(More)
Salmonellae are ubiquitous human pathogens, which pose a danger to the elderly and children. Due to the increased number of outbreaks of human illness associated with the consumption of contaminated products in the USA and many other countries, there is an urgent need to develop rapid assays to detect common food-borne pathogens. This study demonstrates the(More)
We report the results of atomic force microscopy, Fourier-transform infrared spectroscopy, solid-state nuclear magnetic resonance, and molecular dynamics (MD) calculations for amyloid fibrils formed by residues 109-122 of the Syrian hamster prion protein (H1). Our data reveal that H1 fibrils contain no more than two beta-sheet layers. The peptide strands of(More)