Chukwuemeka R. Nwokocha

Javier Palacios2
Fredi Cifuentes2
Ime E. Edoho1
2Javier Palacios
2Fredi Cifuentes
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Apocynin is reported to have antioxidant and NADPH oxidase inhibitor activities. Cadmium toxicity is reported to causes oxidative damage, resulting in vascular dysfunction, reduced bioavailability of nitric oxide (NO) and hypertension. The study aimed to investigate the protective effects of apocynin in cadmium-induced hypertension. Thirty-six (36) adult(More)
Mercury toxicity leads to cell damage in many organs of the body. The authors comparatively examined the ability of different food additives with medicinal properties to protect against mercury (Hg) accumulation in the liver following different treatment interventions and modes of administration. Rats were fed on either 7% w/w Zingiber officinale, 7% w/w(More)
Arsenic trioxide (As2O3) is used clinically in the management of acute promyelocytic leukemia, and the use of electrocardiogram (ECG) in this management is important as arsenic use may cause distortion of the electrical properties with its attendant sequel. We studied the effect of As2O3 on vasomotion in rat aortic rings using isometric tension recordings(More)
CONTEXT Zingiber officinale (Zingiberaceae) is a herb used for culinary and therapeutic purposes due to its anti-inflammatory and antioxidant potentials. OBJECTIVES We examined its protective ability against mercury (Hg), lead (Pb) and cadmium (Cd) accumulation in the liver. MATERIALS #ENTITYSTARTX00026; METHODS Ground Zingiber officinale (7%, w/w of(More)
The effect of vitamin C administration on gastric acid secretion and ulcer in diabetic rats was studied. Vitamin C (200 mg/kg b.w.) was administered to both streptozotocin-induced diabetic and control groups orally for 28 days. Gastric acid secretion was measured and ulcer was induced using ethanol. Histological changes were observed in the stomach. Basal(More)
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