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A quiescent [denoted as Q(G0/G1)] subpopulation was isolated from EMT6/Ro-fed plateau monolayers by centrifugal elutriation. The median Coulter volume of these cells was significantly smaller than that of the original population from which they were elutriated. Using two-step acridine orange staining and dual parameter flow cytometric analysis, over 95% of(More)
Two subpopulations enriched in cells with a G1-like content of DNA were isolated from EMT6/Ro spheroids using centrifugal elutriation. The techniques of two-step acridine orange staining followed by flow cytometry, and continuous [3H]-thymidine labelling agreed qualitatively that one of these subpopulations predominantly consisted of proliferating G1 cells,(More)
This paper addresses the computation of static nonlinear output feedback controllers for increasing the domain of attraction of an equilibrium point of piecewise nonlinear polynomial systems. Specifically, we consider continuous-time dynamical systems where the state space is partitioned into possibly overlapping regions, and where the vector field is(More)
— This paper addresses the estimation of the domain of attraction for a class of hybrid nonlinear systems where the state space is partitioned into several regions. Each region is described by polynomial inequalities, and one of these regions is the complement of the union of all the others in order to ensure complete cover of the state space. The system(More)
This paper studies robust local synchronization in multi-agent systems with time-varying parametric uncertainties constrained in a polytope. In contrast to existing methods with non-convex conditions via using quadratic Lyapunov function (QLF), a new criteria is proposed based on using homogeneous polynomial Lyapunov functions (HPLFs) where the original(More)
The outcome of cancer chemotherapy is determined by an interplay of multiple factors between the host, the tumour, and the drugs administered. Most studies have emphasised the development or selection of drug resistant tumour cells. However, repeated drug treatment of the host may lead to changes (e.g. in pharmacokinetics, host defences, etc.) which can(More)
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