Chuck Miller

Learn More
The availability of ChimeriVax vaccine technology for delivery of flavivirus protective antigens at the time West Nile (WN) virus was first detected in North America in 1999 contributed to the rapid development of the vaccine candidate against WN virus described here. ChimeriVax-Japanese encephalitis (JE), the first live- attenuated vaccine developed with(More)
In large-scale disaster events, infrastructure owners are faced with many challenges in deciding the allocation ofresources for preparation and response actions. This decision process involves building situation awareness, evaluating course of action, and effecting response. This paper describes a modeling and simulation system called CIMS that presents a(More)
University of California at Berkeley, Berkeley, CA USA Smithsonian Institution, Washington D.C. USA University of Florida, Gainesville, FL USA Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research, Bremen, Germany Freie Universität Berlin, Berlin, Germany University of Colorado, Boulder, CO USA Missouri Botanical Garden, Saint Louis, MO(More)
Botanic gardens play key roles in the development and dissemination of plant information resources. Drivers for change have included progress in information technology, growing public expectations of electronic access and international conservation policy. Great advances have been made in the quantity, quality and accessibility of plant information in(More)
Two subjects developed marked elevations in creatine kinase and other serum enzymes associated with mild myalgia during a randomized, double-blind, controlled Phase 1 clinical trial of an investigational live, attenuated vaccine against West Nile virus (ChimeriVax-WN02). One subject had received ChimeriVax-WN02 while the other subject was enrolled in an(More)
Current requirements for control of live viral vaccines, including yellow fever 17D, produced from potentially neurotropic wild-type viruses include tests for neurovirulence in nonhuman primates. We have used yellow fever 17D virus as a live vector for novel flavivirus vaccines (designated ChimeriVax) against dengue, Japanese encephalitis (JE), and West(More)
  • 1