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There is more and more commercial and research interest in location-based web search, i.e. finding web content whose topic is related to a particular place or region. In this type of search, location information should be indexed as well as text information. However, the index of conventional text search engine is set-oriented, while location information is(More)
Accurately and effectively detecting the locations where search queries are truly about has huge potential impact on increasing search relevance. In this paper, we define a search query's dominant location (QDL) and propose a solution to correctly detect it. QDL is geographical location(s) associated with a query in collective human knowledge, i.e., one or(More)
RATIONALE Cyclic AMP signaling plays an important role in memory loss associated with Alzheimer's disease (AD). However, little is known about whether inhibition of phosphodiesterase-4 (PDE4), which increases intracellular cAMP, reverses β-amyloid peptide (Aβ)-induced memory deficits. OBJECTIVE Experiments were performed to demonstrate the effect of the(More)
Protecting privacy in sensor networks poses new challenges because of the potential incompatibilities between new privacy-preserving mechanisms and mechanisms already implemented in sensor networks (such as in-network data aggregation). To address this problem, we propose in this paper a set of new privacy-preservation data aggregation schemes. Different(More)
Recent studies demonstrate that the neuropeptide VGF (nonacronymic)-derived peptide is regulated in the hippocampus by antidepressant therapies. Brain-derived neurotrophic factor (BDNF), tropomyosin-related kinase B (TrkB), cAMP response element-binding protein (CREB) signaling, and monoamine transmitter pathways mediate the behavioral effects of(More)
Rapid pervasion of the web into users' daily lives has put much importance on capturing location-specific information on the web, due to the fact that most human activities occur locally around where a user is located. This is especially true in the increasingly popular mobile and local search environments. Thus, how to correctly and effectively detect(More)
Plants employ two distinct strategies to obtain iron (Fe) from the soil. In Strategy I but not Strategy II plants, Fe limitation invokes ethylene production which regulates Fe deficiency responses. Oryza sativa (rice) is the only graminaceous plant described that possesses a Strategy I-like system for iron uptake as well as the classic Strategy II system.(More)
The Kaczmarz method, or the algebraic reconstruction technique (ART), is a popular method for solving large-scale overdetermined systems of equations. Recently, Strohmer et al. proposed the randomized Kaczmarz algorithm, an improvement that guarantees exponential convergence to the solution. This has spurred much interest in the algorithm and its(More)
β-amyloid (Aβ) peptides play an important role in cognition deficits, neuroinflammation, and apoptosis observed in Alzheimer's disease (AD). Activation of cyclic AMP (cAMP) signalling enhances memory and inhibits inflammatory and apoptotic responses. However, it is not known whether inhibition of phosphodiesterase-4 (PDE4), a critical controller of(More)
Memory deficit is a marker of Alzheimer's disease (AD) that has been highly associated with the dysfunction of cyclic GMP (cGMP) signaling and an ongoing inflammatory process. Phosphodiesterase-5 (PDE5) inhibitors prevent the breakdown of cGMP and are currently studied as a possible target for cognitive enhancement. However, it is still unknown whether(More)