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There is more and more commercial and research interest in location-based web search, i.e. finding web content whose topic is related to a particular place or region. In this type of search, location information should be indexed as well as text information. However, the index of conventional text search engine is set-oriented, while location information is(More)
Accurately and effectively detecting the locations where search queries are truly about has huge potential impact on increasing search relevance. In this paper, we define a search query's dominant location (QDL) and propose a solution to correctly detect it. QDL is geographical location(s) associated with a query in collective human knowledge, i.e., one or(More)
Plant growth and development are strongly influenced by the availability of nutrients in the soil solution. Among them, phosphorus (P) is one of the most essential and most limiting macro-elements for plants. In the environment, plants are often confronted with P starvation as a result of extremely low concentrations of soluble inorganic phosphate (Pi) in(More)
In the yeast Saccharomyces cerevisiae, a working model for nutrient homeostasis in eukaryotes, inorganic phosphate (Pi) homeostasis is regulated by the PHO pathway, a set of phosphate starvation induced genes, acting to optimize Pi uptake and utilization. Among these, a subset of proteins containing the SPX domain has been shown to be key regulators of Pi(More)
Heat stress transcription factors (Hsfs) are the central regulators of defense response to heat stress. We identified a total of 25 rice Hsf genes by genome-wide analysis of rice (Oryza sativa L.) genome, including the subspecies of O. japonica and O. indica. Proteins encoded by OsHsfs were divided into three classes according to their structures. Digital(More)
• Proteins possessing the SPX domain are found in several proteins involved in inorganic phosphate (Pi) transport and signalling in yeast and plants. Although the functions of several SPX-domain protein subfamilies have recently been uncovered, the role of the SPX-MFS subfamily is still unclear. • Using quantitative RT-PCR analysis, we studied the(More)
RATIONALE Cyclic AMP signaling plays an important role in memory loss associated with Alzheimer's disease (AD). However, little is known about whether inhibition of phosphodiesterase-4 (PDE4), which increases intracellular cAMP, reverses β-amyloid peptide (Aβ)-induced memory deficits. OBJECTIVE Experiments were performed to demonstrate the effect of the(More)
Fructose consumption has been recently related to an epidemic of metabolic syndrome, and hyperuricemia plays a pathogenic role in fructose-induced metabolic syndrome. Fructose-fed rats showed hyperuricemia and renal dysfunction with reductions of the urinary uric acid/creatinine ratio and fractional excretion of uric acid (FE(ur)), as well as other features(More)
BACKGROUND AND PURPOSE Thioredoxin-interacting protein (TXNIP), a regulator of cellular oxidative stress, has been associated with activation of NOD-like receptor 3 (NLRP3) inflammasome, inflammation and lipid metabolism, suggesting it has a role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) in diabetes. In this study we investigated(More)
Protecting privacy in sensor networks poses new challenges because of the potential incompatibilities between new privacy-preserving mechanisms and mechanisms already implemented in sensor networks (such as in-network data aggregation). To address this problem, we propose in this paper a set of new privacy-preservation data aggregation schemes. Different(More)