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[Influence of Moxibustion on TLR 4-MyD 88-NF-KB Signal Transduction Pathway of Synovial Tissue in Rheumatoid Arthritis Rats].
Moxibustion intervention can improve pathological changes of the knee-joint synovial membrane tissue in RA rats, which may be related with its effect in inhibiting abnormal activation of TLR 4-MyD 88-NF-κB pathway insynovial tissue. Expand
[Effects of Moxibustion on Expression of STAT 1, SOCS mRNA in Synovium of Rats with Rheumatoid Arthritis].
Moxibustion achieves the effects of anti-inflammation and joint swelling reduction of RA via decrease ofIL-1, increase of IL-2 in serum and up-regulation of STAT 1, SOCS mRNA expression in synovium. Expand
[Toll-like Receptor 4/Nuclear Factor-κB Signaling in Synovial Tissue Is Involved in the Anti-inflammatory Effect of Moxibustion in Rats with Rheumatoid Arthritis].
Moxibustion can reduce the ankle joint swelling in RA rats, which may be closely associated with its effect in down-regulating the expression of IκB, and activation of TLR 4 reduced the anti-inflammatory effect of moxibUSTion intervention. Expand
Progress of mechanism study on rheumatoid arthritis treated by moxibustion
Mainly by its anti-inflammatory and immune effects, moxibustion therapy can be supposed to improve immune functions, inhibit the secretion of the synovial cells factors in the joints, control the proliferation of the synchronous cells, and induce apoptosis of theSynovitis, so as to play a therapeutic role in the treatment of rheumatoid arthritis. Expand
Effects of moxibustion on serum IL-6, IL-8 and TNF-α in rats with experimental rheumatoid arthritis
The effects of moxibustion on serum levels of interleukin (IL)-6, IL-8 and tumor necrosis factor-α (TNF-α) in experimental rheumatoid arthritis (RA) model rats were observed and the relationship between the therapeutic effect of mxibustions on RA and the change in the Toll-like receptor (TLR) signaling pathway was analyzed. Expand