Chrysanthos E. Gounaris

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This paper presents an overview of the research progress in deterministic global optimization during the last decade (1998–2008). It covers the areas of twice continuously differentiable nonlinear optimization, mixed-integer nonlinear optimization, optimization with differential-algebraic models, semi-infinite programming, optimization with grey(More)
Reaction mappings are of fundamental importance to researchers studying the mechanisms of chemical reactions and analyzing biochemical pathways. We have developed an automated method based on integer linear optimization, ILP, to identify optimal reaction mappings that minimize the number of bond changes. An alternate objective function is also proposed that(More)
Designing networks with specified collective properties is useful in a variety of application areas, enabling the study of how given properties affect the behavior of network models, the downscaling of empirical networks to workable sizes, and the analysis of network evolution. Despite the importance of the task, there currently exists a gap in our ability(More)