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The age related effects of 17beta-estradiol (E) supplementation on micturition and contractility of ovariectomized rats (OVX) were evaluated. Studies were carried out in young, 2 month, and mature, 10 month old rats which were distributed into three groups: Sham-operated (SHAM), (OVX), and (OVX+E). Following treatment, urodynamic studies were performed(More)
We localized the temporal and spatial distribution of pressures in the urethra to identify their contribution to continence. With the data obtained we resolved the timing between the passively transmitted and actively generated urethral pressures. Data were obtained from 11 healthy female volunteers, with a mean age of 22 years. Simultaneous measurements of(More)
PURPOSE The pelvic tissue of women with pelvic organ prolapse is stiffer than that of controls but there are scant data on the collagen composition that corresponds to these mechanical properties. We evaluated human vaginal wall stiffness using the novel scanning haptic microscope and correlated these measurements to collagen expression in women with and(More)
What is it that the clinician "feels" during a digital rectal examination? To answer this question, it is necessary to measure the elastic properties of the prostate and verify the stiffness values with histological examination. Therefore, we devised an Elasticity Mapping System to evaluate the elastic properties of various histopathological grades of(More)
BACKGROUND Current measurement tools have difficulty identifying the automatic physiologic processes maintaining continence, and many questions still remain about pelvic floor muscle (PFM) function during automatic events. OBJECTIVE To perform a feasibility study to characterise the displacement, velocity, and acceleration of the PFM and the urethra(More)
control of ureteral peristaltic rate. Am. J. Physiol. 226(6): 1413-1419. l974.-To gain insight into the mechanism responsible for the generation of ureteral peristalsis, a canine experimental model was constructed using manometric methods in the evaluation of the fundamental renal pelvic rhythm and the electrophysiological methods for the characterization(More)
Stiffness is an important parameter in determining the physical properties of living tissue. Recently, considerable biomedical attention has centered on the mechanical properties of living tissues at the single cell level. In the present paper, the Young's modulus of zona pellucida of bovine ovum was calculated using Micro Tactile Sensor (MTS) fabricated(More)