Christos E. Constantinou

Learn More
The diurnal variation in the frequency/volume characteristics of male and female conscious rats was evaluated with reference to fluid consumption and urine production. Baseline values of the micturition volume and frequency of nine male and 10 female SD adult rats were measured over a 24-hour time period. The level of initial hydration conditions was(More)
The incorporation of novel broad band sensory modalities, integrating tactile technology, with visual and auditory signals into the evolution of the next generation of surgical robotic is likely to significantly enhance their utility and safety. In this paper considerations are made of a system, where tactile information together with visual and audio(More)
BACKGROUND Current measurement tools have difficulty identifying the automatic physiologic processes maintaining continence, and many questions still remain about pelvic floor muscle (PFM) function during automatic events. OBJECTIVE To perform a feasibility study to characterise the displacement, velocity, and acceleration of the PFM and the urethra(More)
OBJECTIVE To develop a method to quantify displacement of pelvic structures during contraction of the pelvic floor muscles from transperineal ultrasound images in men and investigate the reliability of the method between days. METHODS Ten healthy male volunteers (aged 28-41 years) attended 2 separate data collection sessions. Ultrasound images were(More)
OBJECTIVES To: (i) visualize the effect of sustained voluntary contractions on the anatomical configuration of the pelvic floor (PF) muscles using magnetic resonance imaging (MRI); (ii) examine the effect of ageing on the range of displacement of the PF contents secondary to contraction and simulating incontinence exercises; and (iii) introduce the concept(More)
In this work, a method to enhance images based on a new artificial life model is presented. The model is inspired on the behaviour of a herbivore organism, when this organism is in a certain environment and selects its food. This organism travels through the image iteratively, selecting the more suitable food and eating parts of it in each iteration. The(More)
AIMS The development of a vaginal probe for the evaluation of the dynamics of pelvic floor function is described. Fundamental criteria in the design of this probe involves the incorporation of a means of assessing whether the isotonic forces closing the vagina are equally distributed or whether they are greater in some directions than others. The aim of(More)
In this review the diagnostic potential of evaluating female pelvic floor muscle (PFM) function using magnetic and ultrasound imaging in the context of urodynamic observations is considered in terms of determining the mechanisms of urinary continence. A new approach is used to consider the dynamics of PFM activity by introducing new parameters derived from(More)
A new in vivo urodynamic animal model was developed to analyze the micturition characteristics of the rat. This model was used to study the modulating effect of pharmacological agents on vesicourethral function, using cystometry and uroflowmetry. Pressure-flow studies were done in 25 female rats anesthetized with urethane. Filling cystometry was recorded(More)